In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …

Phytochemicals have been components of man's diet for millennia and are believed to have
played a significant role in steering the functional development of xenobiotic metabolizing …

Herbs are often administered in combination with therapeutic drugs, raising the potential of
herb-drug interactions. An extensive review of the literature identified reported herb-drug …

The use of botanical dietary supplements has grown steadily over the last 20 years despite
incomplete information regarding active constituents, mechanisms of action, efficacy, and …

Importance of the field: Healthcare practitioners are deeply concerned about drug–herb
interactions and how concurrent administration may affect both the safety and effectiveness …

The use of herbal/botanical products, also referred to as complementary and alternative
medicines (CAM), worldwide enjoys increasing popularity. It appears in particular highly …

Supported by a usage history that predates written records and the perception that “natural”
ensures safety, herbal products have increasingly been incorporated into Western health …

Plants have been used in the treatment of many diseases since ancient times, while also
having served as a major source of modern single compound drugs. Herbal medicines …

Pharmacokinetic interactions often occur as a result of activity changes of drug-metabolizing
and transporting proteins, especially cytochrome P450 (CYP) isoenzymes and P …

Herbal medicines are often used in combination with conventional drugs, and this may give
rise to the potential of harmful herb-drug interactions. This paper updates our knowledge on …