Vaccination is one of the most effective and cost-benefit interventions that prevent the
mortality and reduce morbidity from infectious pathogens. However, the licensed influenza …

Current influenza virus vaccines are annually reformulated to elicit protection by generating
an immune response toward the virus strains that are predicted to circulate in the upcoming …

Please cite this paper as: Sarah C. Gilbert.(2012) Advances in the development of universal
influenza vaccines. Influenza and Other Respiratory Viruses DOI: 10.1111/irv. 12013 …

​ Summary Globally, infection by seasonal influenza viruses causes 3–5 million cases of
severe illness and 290,000–650,000 respiratory deaths each year. Various influenza …

Influenza Vaccines for the Future | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Introduction: Influenza occurs worldwide and causes significant disease burden in terms of
morbidity, associated complications, hospitalizations, and deaths. Vaccination constitutes …

The challenges in successful vaccination against influenza using conventional approaches
lie in their variable efficacy in different age populations, the antigenic variability of the …

The development of vaccines that could provide broad protection against antigenically
variant influenza viruses has long been the ultimate prize in influenza research. Recent …

Outbreaks of influenza A viruses continue to cause morbidity and mortality worldwide. The
global disease burden of influenza is substantial. While antiviral therapies are available …

Several strategies are being pursued to increase the quality and quantity of influenza
vaccines that are used on an annual basis including increasing the immunogenicity of …