Embryonic stem cells (ESCs) hold great promises for treating and studying numerous
devastating diseases. The molecular basis of their potential is not completely understood …

Pluripotency refers to the self‐renewal of undifferentiated embryonic stem cells (ESCs), and
is maintained by a tightly regulated gene regulatory network involving an intricate interplay …

There is increasing evidence that long noncoding RNAs (lncRNAs) are among the main
regulatory factors of stem cell maintenance and differentiation. They act through various …

Pluripotent stem cells have broad applications in regenerative medicine and offer ideal
models for understanding the biological process of embryonic development and specific …

Embryonic Stem cells are widely studied to elucidate the disease and developmental
processes because of their capability to differentiate into cells of any lineage, Pervasive …

Highlights•Cis-and trans-acting lncRNAs are involved in stem cell pluripotency and
reprogramming.•lncRNA-mediated cis regulation of nearby transcription is a prevalent …

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold immense
promise for regenerative medicine due to their abilities to self-renew and to differentiate into …

The most part of our genome encodes for RNA transcripts are never translated into proteins.
These include families of RNA molecules with a regulatory function, which can be arbitrarily …

Because of their capability of differentiation into lineage‐specific cells, stem cells are an
attractive therapeutic modality in regenerative medicine. To develop an effective stem cell …

Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells
occupy a special position in cell biology and Biomedicine, and emerging results show that …