Epitope-based vaccine against influenza

T Ben-Yedidia, R Arnon - Expert review of vaccines, 2007 - Taylor & Francis
The currently available vaccines against influenza are viral strain specific and, hence, their
efficacy is limited when the circulating strain is not the one included in them. We review …

A synthetic adjuvant to enhance and expand immune responses to influenza vaccines

RN Coler, SL Baldwin, N Shaverdian, S Bertholet… - PloS one, 2010 - journals.plos.org
Safe, effective adjuvants that enhance vaccine potency, including induction of neutralizing
Abs against a broad range of variant strains, is an important strategy for the development of …

Efforts to improve the seasonal influenza vaccine

AT Harding, NS Heaton - Vaccines, 2018 - mdpi.com
Influenza viruses infect approximately 20% of the global population annually, resulting in
hundreds of thousands of deaths. While there are Food and Drug Administration (FDA) …

A review of DNA vaccines against influenza

LYY Lee, L Izzard, AC Hurt - Frontiers in immunology, 2018 - frontiersin.org
The challenges of effective vaccination against influenza are gaining more mainstream
attention, as recent influenza seasons have reported low efficacy in annual vaccination …

Influenza viruses and vaccines: the role of vaccine effectiveness studies for evaluation of the benefits of influenza vaccines

CM Trombetta, O Kistner, E Montomoli, S Viviani… - Vaccines, 2022 - mdpi.com
Influenza is a vaccine preventable disease and vaccination remains the most effective
method of controlling the morbidity and mortality of seasonal influenza, especially with …

Is it possible to develop a “universal” influenza virus vaccine? Potential target antigens and critical aspects for a universal influenza vaccine

F Krammer, A García-Sastre… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Influenza viruses cause seasonal epidemics as well as pandemics and are a significant
concern for human health. Current influenza virus vaccines show efficacy when they are …

Advances in vaccine adjuvants

M Singh, D O'Hagan - Nature biotechnology, 1999 - nature.com
Currently, aluminum salts and MF59 are the only vaccine adjuvants approved for human
use. With the development of new-generation vaccines (including recombinant subunit and …

Development of a universal influenza vaccine

LD Estrada, S Schultz-Cherry - The Journal of Immunology, 2019 - journals.aai.org
The severity of the 2017–18 influenza season, combined with the low efficacy for some
vaccine components, highlights the need to improve our current seasonal influenza vaccine …

Vaccine approaches conferring cross-protection against influenza viruses

SV Vemula, EE Sayedahmed, S Sambhara… - Expert review of …, 2017 - Taylor & Francis
Introduction: Annual vaccination is one of the most efficient and cost-effective strategies to
prevent and control influenza epidemics. Most of the currently available influenza vaccines …

Influenza virus: dealing with a drifting and shifting pathogen

H Kim, RG Webster, RJ Webby - Viral immunology, 2018 - liebertpub.com
Numerous modern technological and scientific advances have changed the vaccine
industry. However, nearly 70 years of influenza vaccine usage have passed without …