Tolerogenic dendritic cells (TDC) offer a promising therapeutic potential to ameliorate
autoimmune diseases. Reported to inhibit adaptive immune responses, little is known about …

Dendritic cells (DCs) differentiated in the presence of IL-10 preferentially induce regulatory T-
cells and tolerance. Whether the tolerogenic properties displayed by these DCs (Tol-DCs) …

Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in …

Background The use of tolerogenic DCs is a promising therapeutic strategy for
transplantation and autoimmune disorders. Immunomodulatory DCs are primarily generated …

Background To avert the differentiation of allergen‐specific T h2 cells in atopic individuals is
a major goal in the prevention and therapy of I g E‐mediated allergy. We aimed to compare …

Stimulation of naive mouse dendritic cells (DC) with LPS or Pam 3 CSK 4 (P3C) induces
production of TNF-α via TLR4-or TLR2-signaling. Although tolerance in macrophages has …

In the past, interferon (IFN)-γ and vitamin D3 (vit D3) have both been associated with
induction of tolerogenic characteristics in human dendritic cells (DCs). Although there are …

Dendritic cells (DCs) shape T-cell response patterns and determine early, intermediate, and
late outcomes of immune recognition events. They either facilitate immunostimulation or …

Background Dendritic cells (DC) are main gate-keepers of the immune system, bridging the
innate and adaptive immune system. DCs are able to mature into inflammatory DCs at sites …

LPS tolerance has been investigated extensively in monocytes/macrophages. However, the
LPS restimulation studies are not well documented in dendritic cells (DCs). In the present …