Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

The development of highly effective and durable vaccines against the human malaria
parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor …

While recent progress has been made in reducing malaria mortality with other interventions,
vaccines are still urgently needed to further reduce the incidence of clinical disease …

Malaria vaccine discovery and development follow two principal strategies. Most subunit
vaccines are designed to mimic naturally acquired immunity that develops over years upon …

The development and implementation of a malaria vaccine would constitute a major
breakthrough for global health. Recently, numerous new candidates have entered clinical …

Malaria is a parasitic disease of major global health significance that causes an estimated
2.7 million deaths each year. In this review we describe the burden of malaria and discuss …

With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently
needed intervention. However, the various stages of the malaria parasite lifecycle have …

Malaria vaccine development has rapidly advanced in the past decade. The very first phase
3 clinical trial of the RTS, S vaccine was completed with over 15,000 African infants and …

Vaccines are the most powerful public health tools mankind has created, but malaria
parasites are bigger, more complicated, and wilier than the viruses and bacteria that have …

Malaria is a disease of public health importance in many parts of the world. Currently, there
is no effective way to eradicate malaria, so developing safe, efficient, and cost‐effective …