Following infection, T cells differentiate into a heterogeneous population of effector T cells
that can mediate pathogen clearance. A subset of these effector T cells possesses the ability …

The ability to develop and sustain populations of memory T cells after infection or
immunization is a hallmark of the adaptive immune response and a basis for protective …

Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

One outcome of infection is the formation of long-lived immunological memory, which
provides durable protection from symptomatic re-infection. In response to infection or …

Immunization in the absence of CD4+ T cell help results in defective CD8+ T cell memory,
deficient recall responses and diminished protective immunity. Here we investigated at what …

A critical aim of vaccine‐related research is to identify the mechanisms by which memory T
cells are formed and maintained over long periods of time. In recent years, we have …

The immune system has evolved by continuously increasing its complexity to provide the
host with an advantage over infectious agents. The development of immunological memory …

The developmental pathways of long-lived memory CD8 T cells and the lineage relationship
between memory T cell subsets remain controversial. Although some studies indicate the …

Immunological memory is characterized by the ability to provide protection from secondary
exposure to pathogens. CD8+ memory T cells provide protection from cell-associated …

How and when memory T cells form during an immune response are long-standing
questions. To better understand memory CD8 T cell development, a time course of gene …