The ongoing epizootic of highly pathogenic avian H5N1 influenza and its direct
transmissibility and high pathogenicity in humans has led to renewed interest in the …

The numerous influenza infections that occur every year present a major public health
problem. Influenza vaccines are important for the prevention of the disease; however, their …

Emulsions have a long history of use as potent and effective adjuvants in humans for a
range of vaccines, particularly for influenza. Although older mineral oil-and water-in-oil …

Please cite this paper as: Fox et al.(2012) Adjuvanted pandemic influenza vaccine: variation
of emulsion components affects stability, antigen structure, and vaccine efficacy. Influenza …

With the exception of alum, emulsion-based vaccine adjuvants have been administered to
far more people than any other adjuvant, especially since the 2009 H1N1 influenza …

The use of adjuvants is being explored as a means of improving vaccine immunogenicity.
This is particularly important for the development of vaccines against potential pandemic …

Standard inactivated influenza vaccines are poorly immunogenic in immunologically naive
healthy young children, who are particularly vulnerable to complications from influenza. For …

Influenza is one of the most common causes of human morbidity and mortality that is
preventable by vaccination. Immunization with available vaccines provides incomplete …

Extensive preparation is underway to mitigate the next pandemic influenza outbreak. New
vaccine technologies intended to supplant egg-based production methods are being …

In spite of current influenza vaccines being immunogenic, evolution of the influenza virus
can reduce efficacy and so influenza remains a major threat to public health. One approach …