Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challenges
J Martí-Carreras, P Maes - Virus Genes, 2019 - Springer
The human cytomegalovirus (HCMV) genome was sequenced by hierarchical shotgun
almost 30 years ago. Over these years, low and high passaged strains have been …
almost 30 years ago. Over these years, low and high passaged strains have been …
Genomic and functional characteristics of human cytomegalovirus revealed by next-generation sequencing
The complete genome of human cytomegalovirus (HCMV) was elucidated almost 25 years
ago using a traditional cloning and Sanger sequencing approach. Analysis of the genetic …
ago using a traditional cloning and Sanger sequencing approach. Analysis of the genetic …
A method enabling high-throughput sequencing of human cytomegalovirus complete genomes from clinical isolates
S Sijmons, K Thys, M Corthout, E Van Damme… - PLoS …, 2014 - journals.plos.org
Human cytomegalovirus (HCMV) is a ubiquitous virus that can cause serious sequelae in
immunocompromised patients and in the developing fetus. The coding capacity of the 235 …
immunocompromised patients and in the developing fetus. The coding capacity of the 235 …
Human cytomegalovirus genomes sequenced directly from clinical material: variation, multiple-strain infection, recombination, and gene loss
The genomic characteristics of human cytomegalovirus (HCMV) strains sequenced directly
from clinical pathology samples were investigated, focusing on variation, multiple-strain …
from clinical pathology samples were investigated, focusing on variation, multiple-strain …
High-resolution human cytomegalovirus transcriptome
D Gatherer, S Seirafian… - Proceedings of the …, 2011 - National Acad Sciences
Deep sequencing was used to bring high resolution to the human cytomegalovirus (HCMV)
transcriptome at the stage when infectious virion production is under way, and major …
transcriptome at the stage when infectious virion production is under way, and major …
High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive …
S Sijmons, K Thys, M Mbong Ngwese… - Journal of …, 2015 - Am Soc Microbiol
Human cytomegalovirus is a widespread pathogen of major medical importance. It causes
significant morbidity and mortality in immunocompromised individuals, and congenital …
significant morbidity and mortality in immunocompromised individuals, and congenital …
Long-read sequencing of human cytomegalovirus transcriptome reveals RNA isoforms carrying distinct coding potentials
The human cytomegalovirus (HCMV) is a ubiquitous, human pathogenic herpesvirus. The
complete viral genome is transcriptionally active during infection; however, a large part of its …
complete viral genome is transcriptionally active during infection; however, a large part of its …
Human cytomegalovirus: taking the strain
GWG Wilkinson, AJ Davison, P Tomasec… - Medical microbiology …, 2015 - Springer
In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV),
we reflect on the merits and limitations of the viral strains currently being used to develop …
we reflect on the merits and limitations of the viral strains currently being used to develop …
Functional annotation of human cytomegalovirus gene products: an update
E Van Damme, M Van Loock - Frontiers in microbiology, 2014 - frontiersin.org
Human cytomegalovirus is an opportunistic double-stranded DNA virus with one of the
largest viral genomes known. The 235 kB genome is divided in a unique long (UL) and a …
largest viral genomes known. The 235 kB genome is divided in a unique long (UL) and a …
Antisense transcription in the human cytomegalovirus transcriptome
G Zhang, B Raghavan, M Kotur, J Cheatham… - Journal of …, 2007 - Am Soc Microbiol
Human cytomegalovirus (HCMV) infections are prevalent in human populations and can
cause serious diseases, especially in those with compromised or immature immune …
cause serious diseases, especially in those with compromised or immature immune …