Differential production of IL-12, IFN-α, and IFN-γ by mouse dendritic cell subsets
H Hochrein, K Shortman, D Vremec, B Scott… - The Journal of …, 2001 - journals.aai.org
Dendritic cells (DC) not only stimulate T cells effectively but are also producers of cytokines
that have important immune regulatory functions. In this study we have extended information …
that have important immune regulatory functions. In this study we have extended information …
Interleukin-10-Producing DC-10 Is a Unique Tool to Promote Tolerance Via Antigen-Specific T Regulatory Type 1 Cells
M Comi, G Amodio, S Gregori - Frontiers in immunology, 2018 - frontiersin.org
The prominent role of tolerogenic dendritic cells (tolDCs) in promoting immune tolerance
and the development of efficient methods to generate clinical grade products allow the …
and the development of efficient methods to generate clinical grade products allow the …
Induction of an anti-inflammatory cytokine, IL-10, in dendritic cells after toll-like receptor signaling
R Samarasinghe, P Tailor, T Tamura… - Journal of interferon & …, 2006 - liebertpub.com
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that modulates innate and adaptive
immunity. IL-10 transcripts and the protein were induced in murine bone marrow-derived …
immunity. IL-10 transcripts and the protein were induced in murine bone marrow-derived …
Dendritic cells contribute to the development of atopy by an insufficiency in IL-12 production
N Reider, D Reidera, S Ebner, S Holzmann… - Journal of allergy and …, 2002 - Elsevier
Background: IL-12 is a crucial factor in the development and course of allergic diseases. By
virtue of their IL-12 production, dendritic cells (DCs) are potent inducers of TH1 responses …
virtue of their IL-12 production, dendritic cells (DCs) are potent inducers of TH1 responses …
The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-α production in CD11c+ CD11b+ CD8− dendritic cells
CL Doxsee, TR Riter, MJ Reiter, SJ Gibson… - The Journal of …, 2003 - journals.aai.org
IL-12 and TNF-α production by dendritic cells (DCs) is a critical step in the initiation of local
inflammation and adaptive immune responses. We show in this study that a small molecule …
inflammation and adaptive immune responses. We show in this study that a small molecule …
Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice
S Feau, V Facchinetti, F Granucci, S Citterio… - Blood, 2005 - ashpublications.org
Dendritic cells (DCs) are involved in the initiation and regulation of innate and adaptive
immune responses. Several molecular mechanisms regulate these diverse DC functions …
immune responses. Several molecular mechanisms regulate these diverse DC functions …
Immunoregulation of dendritic cells
The paradigm of tolerogenic/immature versus inflammatory/mature dendritic cells has
dominated the recent literature regarding the role of these antigen-presenting cells in …
dominated the recent literature regarding the role of these antigen-presenting cells in …
Dendritic cells: translating innate to adaptive immunity
RM Steinman, H Hemmi - From innate immunity to immunological memory, 2006 - Springer
The innate immune system provides many ways to quickly resist infection. The twobest-
studieddefenses indendritic cells (DCs) are the productionof protective cytokines—like …
studieddefenses indendritic cells (DCs) are the productionof protective cytokines—like …
Human dendritic cells require exogenous interleukin-12–inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype
CMU Hilkens, P Kalinski, M de Boer… - Blood, The Journal …, 1997 - ashpublications.org
Dendritic cells (DC) are important initiators of specific primary immune responses because
they are the only APC that can efficiently activate naive Th cells. DC have the capacity to …
they are the only APC that can efficiently activate naive Th cells. DC have the capacity to …
TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation
C Qian, X Jiang, H An, Y Yu, Z Guo, S Liu, H Xu, X Cao - Blood, 2006 - ashpublications.org
Regulatory dendritic cells (DCs) play an important role in maintaining peripheral tolerance
or immune homeostasis. Our previous study demonstrated that mature DCs could be driven …
or immune homeostasis. Our previous study demonstrated that mature DCs could be driven …