Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that
produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory …

Dendritic cells (DCs) are pivotal in determining the class of an adaptive immune response.
However, the molecular mechanisms within DCs that determine this decision-making …

The main function of dendritic cells (DC) is to induce the differentiation of naive T
lymphocytes into helper cells producing a large array of lymphokines, including interleukin …

Allergic diseases are often triggered by environmental allergens that induce dominant type 2
immune responses, characterized by the infiltrated T‐helper type 2 (TH2) lymphocytes …

Background Various microbial, inflammatory and immune signals regulate the activation of
dendritic cells (DC), determining their ability to interact with naïve T cells and to produce …

Dendritic cells (DCs) control immune responses by driving potent inflammatory actions
against external and internal threats while generating tolerance to self and harmless …

Higher animals establish host defense by orchestrating innate and adaptive immunity. This
is mediated by professional antigen presenting cells, ie dendritic cells (DCs). DCs can …

Allergic diseases represent a complex innate and adoptive immune response to natural
environmental allergens with Th2-type T cells and allergen-specific IgE predominance …

Toll-like receptors (TLRs) recognise specific molecular signatures of pathogens and trigger
antimicrobial defence responses. Thereby, two independent signalling pathways can be …

Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice,
CD8α+ DC are specialized to cross-prime CD8+ T cells and produce interleukin-12 (IL-12) …