[HTML][HTML] GABAergic system dysfunction in autism spectrum disorders

H Zhao, X Mao, C Zhu, X Zou, F Peng… - Frontiers in cell and …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a series of neurodevelopmental diseases
characterized by two hallmark symptoms, social communication deficits and repetitive …

GABA system dysfunction in autism and related disorders: from synapse to symptoms

S Coghlan, J Horder, B Inkster, MA Mendez… - Neuroscience & …, 2012 - Elsevier
Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by
repetitive behaviours and restricted interests, impairments in social behaviour and relations …

[HTML][HTML] Synaptopathology involved in autism spectrum disorder

S Guang, N Pang, X Deng, L Yang, F He… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

Alterations of GABAergic signaling in autism spectrum disorders

R Pizzarelli, E Cherubini - Neural plasticity, 2011 - Wiley Online Library
Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …

The role of GABAergic neural circuits in the pathogenesis of autism spectrum disorder

J Di, J Li, B O'Hara, I Alberts, L Xiong… - International Journal of …, 2020 - Wiley Online Library
Autism spectrum disorder (ASD) comprises a heterogeneous range of neurodevelopmental
conditions represented by symptoms including, communication and language deficits …

A Common Susceptibility Factor of Both Autism and Epilepsy: Functional Deficiency of GABAA Receptors

JQ Kang, G Barnes - Journal of autism and developmental disorders, 2013 - Springer
Autism and epilepsy are common childhood neurological disorders with a great
heterogeneity of clinical phenotypes as well as risk factors. There is a high co-morbidity of …

Exploring the relationship between cortical GABA concentrations, auditory gamma‐band responses and development in ASD: Evidence for an altered maturational …

RG Port, W Gaetz, L Bloy, DJ Wang, L Blaskey… - Autism …, 2017 - Wiley Online Library
Autism spectrum disorder (ASD) is hypothesized to arise from imbalances between
excitatory and inhibitory neurotransmission (E/I imbalance). Studies have demonstrated E/I …

[HTML][HTML] GABAergic circuit dysfunctions in neurodevelopmental disorders

B Chattopadhyaya, GD Cristo - Frontiers in psychiatry, 2012 - frontiersin.org
GABAergic interneurons control neuronal excitability, integration, and plasticity. Further, they
regulate the generation of temporal synchrony and oscillatory behavior among networks of …

Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities

HY Zoghbi, MF Bear - Cold Spring Harbor perspectives …, 2012 - cshperspectives.cshlp.org
The discovery of the genetic causes of syndromic autism spectrum disorders and intellectual
disabilities has greatly informed our understanding of the molecular pathways critical for …

The neuropathology of autism

GJ Blatt - Scientifica, 2012 - Wiley Online Library
Autism is a behaviorally defined neurodevelopmental disorder that affects over 1% of new
births in the United States and about 2% of boys. The etiologies are unknown and they are …