Murine CMV (MCMV) encodes three viral genes that interfere with Ag presentation (VIPRs)
to CD8 T cells, m04, m06, and m152. Because the functional impact of these genes during …

Natural killer (NK) cells are crucial in the control of cytomegalovirus infections in mice and
humans. Here we show that the viral UL141 gene product has an immunomodulatory …

NKG2D plays a major role in controlling immune responses through the regulation of natural
killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct …

Human cytomegalovirus (HCMV) infection promotes a persistent expansion of a functionally
competent NK‐cell subset expressing the activating CD94/NKG2C receptor. Factors …

The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged
genes (US12-21) with poorly characterized function. We now identify novel natural killer …

Viruses, such as human cytomegalovirus (HCMV), have developed mechanisms to evade
recognition by, and activation of, natural killer (NK) cells, which are cells that provide crucial …

NKG2D is a potent activating receptor expressed on NK cells, NKT cells, γδ T cells, and CD8
T cells. NKG2D recognizes cell surface molecules structurally related to MHC class I …

Natural killer (NK) cells are important effectors of innate immune responses against virally
infected cells and tumors. Since NK cells are the first lymphocyte population to recover after …

Cmv1 was the first mouse cytomegalovirus (MCMV) resistance locus identified in C57BL/6
mice. It encodes Ly49H, a NK cell-activating receptor that specifically recognizes the m157 …

Natural killer (NK) cells show some features of adaptive immunity but have not been studied
at the clonal level. Here, we used retrogenic color-barcoding and single-cell adoptive …