Cellular and synaptic network defects in autism
Many candidate genes are now thought to confer susceptibility to autism spectrum disorders
(ASDs). Here we review four interrelated complexes, each composed of multiple families of …
(ASDs). Here we review four interrelated complexes, each composed of multiple families of …
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses
Autism spectrum disorder (ASD) is a group of developmental disabilities characterized by
impairments in social interaction and communication and restricted and repetitive …
impairments in social interaction and communication and restricted and repetitive …
Pathology and astrocytes in autism
G Vakilzadeh, V Martinez-Cerdeño - Neuropsychiatric Disease and …, 2023 - Taylor & Francis
A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal
studies have focused on investigating the role of neurons in ASD. However, recent studies …
studies have focused on investigating the role of neurons in ASD. However, recent studies …
The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …
Key role for gene dosage and synaptic homeostasis in autism spectrum disorders
Autism spectrum disorders (ASD) are characterized by impairments in reciprocal social
communication, and repetitive, stereotyped verbal and non-verbal behaviors. Genetic …
communication, and repetitive, stereotyped verbal and non-verbal behaviors. Genetic …
The emerging picture of autism spectrum disorder: genetics and pathology
JA Chen, O Peñagarikano, TG Belgard… - Annual Review of …, 2015 - annualreviews.org
Autism spectrum disorder (ASD) is defined by impaired social interaction and
communication accompanied by stereotyped behaviors and restricted interests. Although …
communication accompanied by stereotyped behaviors and restricted interests. Although …
Astrocytes and microglia and their potential link with autism spectrum disorders
F Petrelli, L Pucci, P Bezzi - Frontiers in cellular neuroscience, 2016 - frontiersin.org
The cellular mechanism (s) underlying autism spectrum disorders (ASDs) are not fully
understood although it has been shown that various genetic and environmental factors …
understood although it has been shown that various genetic and environmental factors …
Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling
M Allen, BS Huang, MJ Notaras, A Lodhi… - Molecular …, 2022 - nature.com
The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood.
Cumulative evidence suggests that abnormal synapse function underlies many features of …
Cumulative evidence suggests that abnormal synapse function underlies many features of …
Autism spectrum disorders: multiple routes to, and multiple consequences of, abnormal synaptic function and connectivity
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders of genetic and environmental etiologies. Some ASD cases are syndromic …
disorders of genetic and environmental etiologies. Some ASD cases are syndromic …
Sensorimotor dysfunctions as primary features of autism spectrum disorders
MW Mosconi, JA Sweeney - Science China Life Sciences, 2015 - Springer
Motor impairments in autism spectrum disorders (ASD) have received far less research
attention than core socialcommunication and cognitive features. Yet, behavioral …
attention than core socialcommunication and cognitive features. Yet, behavioral …