Permethrin resistance in Aedes aegypti: Genomic variants that confer knockdown resistance, recovery, and death

K Saavedra-Rodriguez, CL Campbell, S Lozano… - PLoS …, 2021 - journals.plos.org
Pyrethroids are one of the few classes of insecticides available to control Aedes aegypti, the
major vector of dengue, chikungunya, and Zika viruses. Unfortunately, evolving mechanisms …

Pyrethroid resistance in Aedes aegypti and Aedes albopictus: Important mosquito vectors of human diseases

LB Smith, S Kasai, JG Scott - Pesticide biochemistry and physiology, 2016 - Elsevier
Aedes aegypti and A. albopictus mosquitoes are vectors of important human disease
viruses, including dengue, yellow fever, chikungunya and Zika. Pyrethroid insecticides are …

Combined target site (kdr) mutations play a primary role in highly pyrethroid resistant phenotypes of Aedes aegypti from Saudi Arabia

AM Al Nazawi, J Aqili, M Alzahrani, PJ McCall… - Parasites & vectors, 2017 - Springer
Background Pyrethroid resistance is a threat to effective vector control of Aedes aegypti, the
vector of dengue, Zika and other arboviruses, but there are many major knowledge gaps on …

Assessing the Effects of Aedes aegypti kdr Mutations on Pyrethroid Resistance and Its Fitness Cost

LP Brito, JGB Linss, TN Lima-Camara, TA Belinato… - PloS one, 2013 - journals.plos.org
Pyrethroids are the most used insecticide class worldwide. They target the voltage gated
sodium channel (NaV), inducing the knockdown effect. In Aedes aegypti, the main dengue …

First report of V1016I, F1534C and V410L kdr mutations associated with pyrethroid resistance in Aedes aegypti populations from Niamey, Niger

AA Maiga, A Sombié, N Zanré, F Yaméogo, S Iro… - Plos one, 2024 - journals.plos.org
Background Ae. aegypti is the vector of important μ arboviruses, including dengue, Zika,
chikungunya and yellow fever. Despite not being specifically targeted by insecticide-based …

Knockdown Resistance Mutations in Aedes aegypti (Diptera: Culicidae) From Puerto Rico

G Ponce-García, S Del Río-Galvan… - Journal of medical …, 2016 - academic.oup.com
Permethrin resistance is widespread in Aedes aegypti (L.), the main dengue, zika, and
chikungunya virus vector in Latin America and the Caribbean. A common mechanism of …

Mechanisms of Pyrethroid Resistance in the Dengue Mosquito Vector, Aedes aegypti: Target Site Insensitivity, Penetration, and Metabolism

S Kasai, O Komagata, K Itokawa, T Shono… - PLoS neglected …, 2014 - journals.plos.org
Aedes aegypti is the major vector of yellow and dengue fevers. After 10 generations of adult
selection, an A. aegypti strain (SP) developed 1650-fold resistance to permethrin, which is …

Permethrin Resistance in Aedes aegypti Affects Aspects of Vectorial Capacity

TY Chen, CT Smartt, D Shin - Insects, 2021 - mdpi.com
Simple Summary Pyrethroids have been applied as a major type of insecticide targeted at
mosquitoes, many of which are key vectors in the transmission of several flaviviruses …

Identification of Molecular Determinants of Resistance to Pyrethroid Insecticides in Aedes aegypti (Diptera: Culicidae) Populations in California, USA

KA Liebman, SA Billeter, MH Yoshimizu… - Journal of Medical …, 2019 - academic.oup.com
The first breeding populations of Aedes aegypti (Linnaeus) were identified in California in
2013, and have since been detected in 13 counties. Recent studies suggest two …

A mutation in the voltage‐gated sodium channel gene associated with pyrethroid resistance in Latin American Aedes aegypti

K Saavedra‐Rodriguez… - Insect molecular …, 2007 - Wiley Online Library
Pyrethroids are commonly used as mosquito adulticides and evolution of resistance to these
compounds is a major threat to public health.'Knockdown resistance'to pyrethroids (kdr) is …