Memory CD8 T cells, essential for defense against intracellular pathogens, are
heterogeneous with respect to phenotype and function. Constitutively lytic effector memory …

After the resolution of an immune response, antigen-specific memory T cells persist at many
sites in the body. The antigen-specific memory T-cell pool includes memory T cells that …

CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is
known about the effector function of Th cells in combating pathogens and promoting …

Generating long-lasting, protective CD8+ T-cell memory via vaccination is critical for
combating infectious diseases. Advances in the past year have provided many new insights …

CD8 T cells contribute to clearance and long-term protection following acute infection with
certain viruses, bacteria, and protozoa, and may play an important role in tumor immunity …

CD8 T cells comprise a powerful branch of the adaptive immune system, yet were not
formally recognized until long after the discovery of antibody. CD8 T cells contribute to the …

The induction of adaptive immunological memory, mediated by T and B cells, plays an
important role in protective immunity to pathogens induced by previous infections or …

Adequate antigen stimulation can lead to permanent modifications of primed cells and to the
generation of memory T cells that have astonishingly improved capacities to deal with …

Tissue-resident memory T (Trm) cells are a subset of recently identified memory T cells that
mainly reside and serve as sentinels in non-lymphoid peripheral tissues. Unlike the well …

Immunologic memory is the adaptive immune system's powerful ability to remember a
previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It …