Immunological memory provides the basis for successful vaccines. It is important to
understand the properties of memory cells. There is much known about the phenotype and …

Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

A critical aim of vaccine‐related research is to identify the mechanisms by which memory T
cells are formed and maintained over long periods of time. In recent years, we have …

Immunological memory provides rapid protection to pathogens previously encountered
through infection or vaccination. CD 4 T‐cells play a central role in all adaptive immune …

Immunological memory is a hallmark of adaptive immunity, and understanding T cell
memory will be central to the development of effective cell-mediated vaccines. The …

An important goal of vaccination strategies is to elicit long term, effective immunity. Therefore
it is imperative to define the parameters that regulate the development and preservation of …

CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly
due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli …

Memory CD8+ T cells were originally thought to exist as two populations (effector and
central memory). In recent years, a third population called resident memory T cells has been …

Immunological memory crucially depends on CD4 T cells. In contrast with B cells, we find no
decisive evidence that CD4 T cells are permanently altered by antigen stimulation. We …

Memory CD8+ T cells are an important component of the adaptive immune response against
many infections, and understanding how Ag-specific memory CD8+ T cells are generated …