Impact of sex and reproductive status on memory circuitry structure and function in early midlife using structural covariance analysis

J Seitz, M Kubicki, EG Jacobs… - Human brain …, 2019 - Wiley Online Library
Research on age‐related memory alterations traditionally targets individuals aged≥ 65
years. However, recent studies emphasize the importance of early aging processes. We …

The impact of age on prefrontal cortex integrity during spatial working memory retrieval

M Toepper, HJ Markowitsch, H Gebhardt, T Beblo… - Neuropsychologia, 2014 - Elsevier
Healthy aging is accompanied by a decline in spatial working memory that is related to
functional cerebral changes within the spatial working memory network. In the last decade …

Age-effects on associative object–location memory

O Meulenbroek, RPC Kessels, M De Rover… - Brain research, 2010 - Elsevier
Aging is accompanied by an impairment of associative memory. The medial temporal lobe
and fronto-striatal network, both involved in associative memory, are known to decline …

Healthy aging attenuates task-related specialization in the human medial temporal lobe

TZ Ramsøy, MG Liptrot, A Skimminge, TE Lund… - Neurobiology of …, 2012 - Elsevier
Recent research on aging has established important links between the neurobiology of
normal aging and age-related decline in episodic memory, yet the exact nature of this …

Increasing memory load modulates regional brain activity in older adults as measured by fMRI

JR Petrella, BA Townsend, AP Jha… - The Journal of …, 2005 - Am Neuropsych Assoc
Several recent studies using functional magnetic resonance imaging (fMRI) during
recognition memory tests have suggested that the ability to neuromodulate as a function of …

Effects of aging on hippocampal and anterior temporal activations during successful retrieval of memory for face–name associations

T Tsukiura, A Sekiguchi, Y Yomogida… - Journal of Cognitive …, 2011 - direct.mit.edu
Memory for face–name associations is an important type of memory in our daily lives, and
often deteriorates in older adults. Although difficulty retrieving face–name associations is …

Hippocampal contributions to novel spatial learning are both age-related and age-invariant

L Zheng, Z Gao, S Doner, A Oyao… - Proceedings of the …, 2023 - National Acad Sciences
Older adults show declines in spatial memory, although the extent of these alterations is not
uniform across the healthy older population. Here, we investigate the stability of neural …

Volumetric correlates of spatiotemporal working and recognition memory impairment in aged rhesus monkeys

JL Shamy, C Habeck, PR Hof, DG Amaral… - Cerebral …, 2011 - academic.oup.com
Spatiotemporal and recognition memory are affected by aging in humans and macaque
monkeys. To investigate whether these deficits are coupled with atrophy of memory-related …

Spatial memory—a unique window into healthy and pathological aging

T Wolbers, PA Dudchenko, ER Wood - Frontiers in aging …, 2014 - frontiersin.org
The world's population is aging at an unprecedented rate, because the number of people
aged over 60 will rise from 784 million in 2011 to 2 billion by 2050. Such a dramatic increase …

Aging and the neural correlates of source memory: over-recruitment and functional reorganization

J Spaniol, C Grady - Neurobiology of aging, 2012 - Elsevier
Behavioral evidence suggests that memory for context (ie, source memory) is more
vulnerable to age-related decline than item memory. It is not clear, however, whether this …