Results of a “GWAS plus:” general cognitive ability is substantially heritable and massively polygenic

RM Kirkpatrick, M McGue, WG Iacono, MB Miller… - PloS one, 2014 - journals.plos.org
We carried out a genome-wide association study (GWAS) for general cognitive ability (GCA)
plus three other analyses of GWAS data that aggregate the effects of multiple single …

Low-frequency copy-number variants and general cognitive ability: No evidence of association

RM Kirkpatrick, M McGue, WG Iacono, MB Miller… - Intelligence, 2014 - Elsevier
Although twin, family, and adoption studies have shown that general cognitive ability (GCA)
is substantially heritable, GWAS has not uncovered a genetic polymorphism replicably …

Why genome-wide associations with cognitive ability measures are probably spurious

K Richardson, MC Jones - New Ideas in Psychology, 2019 - Elsevier
Much time and effort, as well as funding, is being devoted to Genome Wide Association
Studies (GWAS) for identifying genetic causes of variation (single nucleotide polymorphisms …

Genome‐wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays

LM Butcher, OSP Davis, IW Craig… - Genes, Brain and …, 2008 - Wiley Online Library
General cognitive ability (g), which refers to what cognitive abilities have in common, is an
important target for molecular genetic research because multivariate quantitative genetic …

A three-stage genome-wide association study of general cognitive ability: hunting the small effects

OSP Davis, LM Butcher, SJ Docherty, EL Meaburn… - Behavior genetics, 2010 - Springer
Childhood general cognitive ability (g) is important for a wide range of outcomes in later life,
from school achievement to occupational success and life expectancy. Large-scale …

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

JW Trampush, T Lencz, E Knowles… - American Journal of …, 2015 - Wiley Online Library
Cognitive deficits and reduced educational achievement are common in psychiatric illness;
understanding the genetic basis of cognitive and educational deficits may be informative …

Pathfinder: A gamified measure to integrate general cognitive ability into the biological, medical, and behavioural sciences

M Malanchini, K Rimfeld, A Gidziela, R Cheesman… - Molecular …, 2021 - nature.com
Genome-wide association (GWA) studies have uncovered DNA variants associated with
individual differences in general cognitive ability (g), but these are far from capturing …

A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups

R Plomin, L Hill, IW Craig, P McGuffin, S Purcell… - Behavior genetics, 2001 - Springer
All measures of cognitive processes correlate moderately at the phenotypic level and
correlate substantially at the genetic level. General cognitive ability (g) refers to what diverse …

Polygenic scores for cognitive abilities and their association with different aspects of general intelligence—a deep phenotyping approach

E Genç, C Schlüter, C Fraenz, L Arning, D Metzen… - Molecular …, 2021 - Springer
Intelligence is a highly polygenic trait and genome-wide association studies (GWAS) have
identified thousands of DNA variants contributing with small effects. Polygenic scores (PGS) …

GWAS and cognitive abilities: Why correlations are inevitable and meaningless: GWA studies to identify genetic factors for educational achievements largely ignore …

K Richardson - EMBO reports, 2017 - embopress.org
association studies (GWAS) are a relatively new and powerful tool to identify gene variants
involved in human variation. The method scans the whole genome for small genetic …