Predicting educational achievement from DNA
A genome-wide polygenic score (GPS), derived from a 2013 genome-wide association
study (N= 127,000), explained 2% of the variance in total years of education (EduYears). In …
study (N= 127,000), explained 2% of the variance in total years of education (EduYears). In …
Phenome-wide analysis of genome-wide polygenic scores
Genome-wide polygenic scores (GPS), which aggregate the effects of thousands of DNA
variants from genome-wide association studies (GWAS), have the potential to make genetic …
variants from genome-wide association studies (GWAS), have the potential to make genetic …
Multi-polygenic score approach to trait prediction
A primary goal of polygenic scores, which aggregate the effects of thousands of trait-
associated DNA variants discovered in genome-wide association studies (GWASs), is to …
associated DNA variants discovered in genome-wide association studies (GWASs), is to …
Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N= 112 151)
People's differences in cognitive functions are partly heritable and are associated with
important life outcomes. Previous genome-wide association (GWA) studies of cognitive …
important life outcomes. Previous genome-wide association (GWA) studies of cognitive …
Polygenic score for educational attainment captures DNA variants shared between personality traits and educational achievement.
E Smith-Woolley, S Selzam… - Journal of Personality and …, 2019 - psycnet.apa.org
Genome-wide polygenic scores (GPS) can be used to predict individual genetic risk and
resilience. For example, a GPS for years of education (EduYears) explains substantial …
resilience. For example, a GPS for years of education (EduYears) explains substantial …
Genomic prediction of cognitive traits in childhood and adolescence
Recent advances in genomics are producing powerful DNA predictors of complex traits,
especially cognitive abilities. Here, we leveraged summary statistics from the most recent …
especially cognitive abilities. Here, we leveraged summary statistics from the most recent …
Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs
One of the best predictors of children's educational achievement is their family's
socioeconomic status (SES), but the degree to which this association is genetically mediated …
socioeconomic status (SES), but the degree to which this association is genetically mediated …
Why genome-wide associations with cognitive ability measures are probably spurious
K Richardson, MC Jones - New Ideas in Psychology, 2019 - Elsevier
Much time and effort, as well as funding, is being devoted to Genome Wide Association
Studies (GWAS) for identifying genetic causes of variation (single nucleotide polymorphisms …
Studies (GWAS) for identifying genetic causes of variation (single nucleotide polymorphisms …
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N= 112 151) and 24 GWAS consortia
Causes of the well-documented association between low levels of cognitive functioning and
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
Genome-wide association studies: a primer
There have been nearly 400 genome-wide association studies (GWAS) published since
2005. The GWAS approach has been exceptionally successful in identifying common …
2005. The GWAS approach has been exceptionally successful in identifying common …