Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction

PA Demange, M Malanchini, TT Mallard, P Biroli… - Nature …, 2021 - nature.com
Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome …

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

JW Trampush, T Lencz, E Knowles… - American Journal of …, 2015 - Wiley Online Library
Cognitive deficits and reduced educational achievement are common in psychiatric illness;
understanding the genetic basis of cognitive and educational deficits may be informative …

Pathfinder: A gamified measure to integrate general cognitive ability into the biological, medical, and behavioural sciences

M Malanchini, K Rimfeld, A Gidziela, R Cheesman… - Molecular …, 2021 - nature.com
Genome-wide association (GWA) studies have uncovered DNA variants associated with
individual differences in general cognitive ability (g), but these are far from capturing …

Genome‐wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays

LM Butcher, OSP Davis, IW Craig… - Genes, Brain and …, 2008 - Wiley Online Library
General cognitive ability (g), which refers to what cognitive abilities have in common, is an
important target for molecular genetic research because multivariate quantitative genetic …

Polygenic scores for cognitive abilities and their association with different aspects of general intelligence—a deep phenotyping approach

E Genç, C Schlüter, C Fraenz, L Arning, D Metzen… - Molecular …, 2021 - Springer
Intelligence is a highly polygenic trait and genome-wide association studies (GWAS) have
identified thousands of DNA variants contributing with small effects. Polygenic scores (PGS) …

[PDF][PDF] Factor analysis of population allele frequencies as a simple, novel method of detecting signals of recent polygenic selection: The example of educational …

D Piffer - Mankind Quarterly, 2013 - endchan.net
Weak widespread (polygenic) selection is a mechanism that acts on multiple SNPs
simultaneously. The aim of this paper is to suggest a methodology to detect signals of …

Common genetic variation and performance on standardized cognitive tests

ET Cirulli, D Kasperavičiūtė, DK Attix… - European Journal of …, 2010 - nature.com
One surprising feature of the recently completed waves of genome-wide association studies
is the limited impact of common genetic variation in individually detectable polymorphisms …

A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups

R Plomin, L Hill, IW Craig, P McGuffin, S Purcell… - Behavior genetics, 2001 - Springer
All measures of cognitive processes correlate moderately at the phenotypic level and
correlate substantially at the genetic level. General cognitive ability (g) refers to what diverse …

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N= 112 151)

G Davies, RE Marioni, DC Liewald, WD Hill… - Molecular …, 2016 - nature.com
People's differences in cognitive functions are partly heritable and are associated with
important life outcomes. Previous genome-wide association (GWA) studies of cognitive …

A polygenic score for higher educational attainment is associated with larger brains

ML Elliott, DW Belsky, K Anderson, DL Corcoran… - Cerebral …, 2019 - academic.oup.com
People who score higher on intelligence tests tend to have larger brains. Twin studies
suggest the same genetic factors influence both brain size and intelligence. This has led to …