The shared genetic basis of educational attainment and cerebral cortical morphology
Individual differences in educational attainment are linked to differences in intelligence, and
predict important social, economic, and health outcomes. Previous studies have found …
predict important social, economic, and health outcomes. Previous studies have found …
PGMRA: a web server for (phenotype× genotype) many-to-many relation analysis in GWAS
It has been proposed that single nucleotide polymorphisms (SNPs) discovered by genome-
wide association studies (GWAS) account for only a small fraction of the genetic variation of …
wide association studies (GWAS) account for only a small fraction of the genetic variation of …
The heritability of general cognitive ability increases linearly from childhood to young adulthood
Although common sense suggests that environmental influences increasingly account for
individual differences in behavior as experiences accumulate during the course of life, this …
individual differences in behavior as experiences accumulate during the course of life, this …
Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations
Polygenic scores (PGS) have been widely used to predict disease risk using variants
identified from genome-wide association studies (GWAS). To date, most GWAS have been …
identified from genome-wide association studies (GWAS). To date, most GWAS have been …
Genome-wide association studies: hypothesis-“free” or “engaged”?
GD Kitsios, E Zintzaras - Translational Research, 2009 - Elsevier
The advent of the first wave of genome-wide association studies (GWAS) provided a new
conceptual framework in the search for variants underlying common disorders: a massive …
conceptual framework in the search for variants underlying common disorders: a massive …
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
JW Trampush, MLZ Yang, J Yu, E Knowles… - Molecular …, 2017 - nature.com
The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …
many other fields in terms of gene discovery using genome-wide association study (GWAS) …
Genetics, environment and cognitive abilities: review and work in progress towards a genome scan for quantitative trait locus associations using DNA pooling
R Plomin, I Craig - The British Journal of Psychiatry, 2001 - cambridge.org
BackgroundMultivariate genetic research indicates that genetic effects on diverse cognitive
abilities are general rather than specific or modular. General cognitive ability (g), a key factor …
abilities are general rather than specific or modular. General cognitive ability (g), a key factor …
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence
Intelligence, or general cognitive function, is phenotypically and genetically correlated with
many traits, including a wide range of physical, and mental health variables. Education is …
many traits, including a wide range of physical, and mental health variables. Education is …
GWIS: genome-wide inferred statistics for functions of multiple phenotypes
Here we present a method of genome-wide inferred study (GWIS) that provides an
approximation of genome-wide association study (GWAS) summary statistics for a variable …
approximation of genome-wide association study (GWAS) summary statistics for a variable …
Stability of polygenic scores across discovery genome-wide association studies
Polygenic scores (PGS) are commonly evaluated in terms of their predictive accuracy at the
population level by the proportion of phenotypic variance they explain. To be useful for …
population level by the proportion of phenotypic variance they explain. To be useful for …