Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies

C Palmer, I Pe'er - PLoS genetics, 2017 - journals.plos.org
Genome-wide association studies (GWAS) have identified hundreds of SNPs responsible for
variation in human quantitative traits. However, genome-wide-significant associations often …

Interactions between socioeconomic status and components of variation in cognitive ability

E Turkheimer, EE Horn - Behavior genetics of cognition across the lifespan, 2013 - Springer
We have proposed that differences in the heritability of cognitive ability as a function of
socioeconomic status (SES) be called the Scarr-Rowe interaction, after the investigator who …

Genetics of intelligence

IJ Deary, FM Spinath, TC Bates - European Journal of Human Genetics, 2006 - nature.com
This article provides an overview of the biometric and molecular genetic studies of human
psychometric intelligence. In the biometric research, special attention is given to the …

Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?

AM Casto, MW Feldman - PLoS genetics, 2011 - journals.plos.org
Genome-wide association studies (GWAS) have identified more than 2,000 trait-SNP
associations, and the number continues to increase. GWAS have focused on traits with …

Brain Catalog: a comprehensive resource for the genetic landscape of brain-related traits

S Pan, H Kang, X Liu, S Lin, N Yuan… - Nucleic Acids …, 2023 - academic.oup.com
A broad range of complex phenotypes are related to dysfunctions in brain (hereafter referred
to as brain-related traits), including various mental and behavioral disorders and diseases of …

Genome-wide strategies for discovering genetic influences on cognition and cognitive disorders: methodological considerations

SG Potkin, JA Turner, G Guffanti, A Lakatos… - Cognitive …, 2009 - Taylor & Francis
Introduction. Genes play a well-documented role in determining normal cognitive function.
This paper focuses on reviewing strategies for the identification of common genetic variation …

Pleiotropy across academic subjects at the end of compulsory education

K Rimfeld, Y Kovas, PS Dale, R Plomin - Scientific reports, 2015 - nature.com
Research has shown that genes play an important role in educational achievement. A key
question is the extent to which the same genes affect different academic subjects before and …

Estimating effects of parents' cognitive and non-cognitive skills on offspring education using polygenic scores

PA Demange, JJ Hottenga, A Abdellaoui… - Nature …, 2022 - nature.com
Understanding how parents' cognitive and non-cognitive skills influence offspring education
is essential for educational, family and economic policy. We use genetics (GWAS-by …

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

CA Rietveld, T Esko, G Davies… - Proceedings of the …, 2014 - National Acad Sciences
We identify common genetic variants associated with cognitive performance using a two-
stage approach, which we call the proxy-phenotype method. First, we conduct a genome …

Can we validate the results of twin studies? A census-based study on the heritability of educational achievement

I Schwabe, L Janss, SPM Van den Berg - Frontiers in Genetics, 2017 - frontiersin.org
As for most phenotypes, the amount of variance in educational achievement explained by
SNPs is lower than the amount of additive genetic variance estimated in twin studies. Twin …