Aim: The aim of this pilot study was to compare the heteroplasmy levels of specific
mitochondrial (mt) DNA mutations in human buccal epithelial and whole blood cells in …

The search for markers of predisposition to atherosclerosis development is very important for
early identification of individuals with a high risk of cardiovascular disease. The aim of the …

Mitochondria have long been known to play a critical role in maintaining the bioenergetic
status of cells under physiological conditions. It was also recognized early in mitochondrial …

The term atherosclerosis refers to the condition of deposition of lipids and other substances
in and on the artery walls, called as plaque that restricts the normal blood flow. The plaque …

Genetic predisposition is of great importance among other risk factors of certain socially
significant chronic non-inflammatory diseases. Changes in both nuclear and mitochondrial …

Mitochondrial DNA (mtDNA), that curious and ancient genomic relic from the birth of the first
eukaryotes, has surfaced once again in a context pertinent to cardiovascular biology and …

Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …

As a leading contributor to coronary artery disease (CAD) and stroke, atherosclerosis has
become one of the major cardiovascular diseases (CVD) negatively impacting patients …

Longer life span and increased prevalence of chronic, noncommunicable, inflammatory
diseases fuel cardiovascular mortality. The microcirculation is central in the cross talk …

Atherosclerosis is one of the leading causes of morbidity and mortality in the Western world.
Although the clinical manifestations of this disease are well documented, the etiology and …