Novel therapies in Takayasu arteritis

F Regola, M Uzzo, P Toniati, B Trezzi, RA Sinico… - Frontiers in …, 2022 - frontiersin.org
Takayasu Arteritis (TAK) is a large-vessel vasculitis that preferentially involves the aorta and
its primary branches. Cardiac involvement is frequent in TAK and is a major determinant of …

Efficacy of biological-targeted treatments in Takayasu arteritis: multicenter, retrospective study of 49 patients

A Mekinian, C Comarmond, M Resche-Rigon… - Circulation, 2015 - Am Heart Assoc
Background—The goal of this work was to assess the safety and efficacy of biologics (ie,
tumor necrosis factor-α antagonists and tocilizumab) in patients with Takayasu arteritis …

Tumor necrosis factor alpha inhibitors in patients with Takayasu's arteritis refractory to standard immunosuppressive treatment: cases series and review of the …

PI Novikov, IO Smitienko, SV Moiseev - Clinical rheumatology, 2013 - Springer
The objective of this study was to report the long-term use of tumor necrosis factor (TNF)
inhibitors in case series of patients with Takayasu's arteritis refractory to standard …

Effectiveness and safety of adalimumab compared with leflunomide in patients with Takayasu arteritis: a retrospective cohort study

F Peron Filho, A de Souza Moreira, ALF Janes… - RMD open, 2024 - rmdopen.bmj.com
Objective This study aims to evaluate the effectiveness and safety of adalimumab (ADA)
compared with leflunomide (LEF) in patients with Takayasu arteritis (TAK). Method A …

Biologic treatments in Takayasu's arteritis: a comparative study of tumor necrosis factor inhibitors and tocilizumab

F Alibaz-Oner, S Kaymaz-Tahra, Ö Bayındır… - Seminars in Arthritis and …, 2021 - Elsevier
Objective To compare the treatment outcomes of TNF inhibitors and tocilizumab (TCZ) in
patients with Takayasu arteritis. Methods Takayasu arteritis patients who were refractory to …

[PDF][PDF] Refractory Takayasu arteritis successfully treated with infliximab.

S Maffei, M Di Renzo, S Santoro… - European Review for …, 2009 - europeanreview.org
Takayasu arteritis (TA) is a chronic inflammatory disease of large arteries which
progressively develop stenosis, occlusion or aneurismal degeneration. Proinflammatory …

Tumor necrosis factor inhibitors in patients with Takayasu arteritis: experience from a referral center with long‐term followup

J Schmidt, TA Kermani, AK Bacani… - Arthritis Care & …, 2012 - Wiley Online Library
Objective To report a single‐center experience with the use of tumor necrosis factor (TNF)
inhibitors in patients with Takayasu arteritis (TA). Methods We retrospectively studied a …

Interleukin 6 targeting in refractory Takayasu arteritis: serial noninvasive imaging is mandatory to monitor efficacy

T Youngstein, JC Mason - The Journal of Rheumatology, 2013 - jrheum.org
Takayasu arteritis (TA) is a true orphan disease. There are no published controlled clinical
trials and the evidence on which to develop management strategies and therapeutic …

Treatment efficacy and safety of adalimumab versus tocilizumab in patients with active and severe Takayasu arteritis: an open-label study

J Wang, X Kong, L Ma, Z Ding, H Chen, R Chen… - …, 2024 - academic.oup.com
Objective This study aimed to compare the efficacy and safety of adalimumab (ADA) vs
tocilizumab (TCZ) in patients with Takayasu arteritis (TAK). Methods This was a randomized …

Comment on: Treatment efficacy and safety of adalimumab versus tocilizumab in patients with active and severe Takayasu arteritis

DP Misra - Rheumatology, 2024 - academic.oup.com
DEAR EDITOR, The recent trial comparing adalimumab with tocilizumab in patients with
severe, active Takayasu arteritis (TAK) addresses an important research question [1]. The …