The immunological potential of animal-derived tissues and organs is the critical hurdle to
increasing their clinical implementation. Glutaraldehyde-fixation cross-links proteins in …

Decellularized extracellular matrix scaffold, widely utilized for organ engineering, often
undergoes matrix decomposition after transplantation and produces byproducts that cause …

Antigenicity remains the primary barrier towards expanding the use of unfixed xenogeneic
biomaterials in clinical applications. An unfixed xenogeneic biomaterial devoid of …

Mesenchymal stem cells (MSCs) have great therapeutic potential for tissue engineering and
regenerative medicine due to their multipotency and paracrine functions. However, shortly …

Tissue or organ regeneration using xenogeneic matrices is a promising approach to
address the shortage of donor matrices for allotransplantation. Success of such approach …

Foreign body response (FBR) to biomaterials compromises the function of implants and
leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that …

Seriously compromised function of some organs can only be restored by transplantation.
Due to the shortage of human donors, the need to find another source of organs is of primary …

Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Cardiac extracellular matrix (cECM) scaffolds are promising biomaterials for reconstructive
surgery applications since they possess the structure/function properties of native tissue …

Designing scaffolds that can regulate the innate immune response and promote
vascularized bone regeneration holds promise for bone tissue engineering. Herein …