Despite advances in experimental and theoretical neuroscience, we are still trying to identify
key biophysical details that are important for characterizing the operation of brain circuits …

Neural network models are potential tools for improving our understanding of complex brain
functions. To address this goal, these models need to be neurobiologically realistic …

The advent of powerful perturbation tools, such as optogenetics, has created new frontiers
for probing causal dependencies in neural and behavioral states. These approaches have …

Remarkable progress has come from whole-brain models linking anatomy and function.
Paradoxically, it is not clear how a neuronal dynamical system running in the fixed human …

In many experiments, neuroscientists tightly control behavior, record many trials, and obtain
trial-averaged firing rates from hundreds of neurons in circuits containing billions of …