INTRODUCTION An inherited component to schizophrenia has been long established and
even noted by Emil Kraepelin in his classical textbook on psychiatry (1). Since Kraepelin´ s …

This chapter describes efforts that attempt to synthesize some of the evidence that bears on
understanding the causes of schizophrenia. Evidence from classical genetic epidemiology …

This article gives an overview of genetic and environmental risk factors for schizophrenia.
The presence of certain molecular, biological, and psychosocial factors at certain points in …

Genetic epidemiological studies indicate that schizophrenia is a complexly inherited
disorder, whereby multiple genes, additively and in interaction with environmental factors …

Schizophrenia is one of the most common, devastating, and least understood
neuropsychiatric illnesses present in the human population. Despite decades of research …

The most important risk factor for schizophrenia is a positive family history, but only a
minority of people with schizophrenia have an affected relative and no single gene of large …

Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …

Nature and nurture are not separate. Instead it is important to investigate the interplay
between genes and environment and how they influence on another. To an important …

Schizophrenia (SCZ) has a heritability of about 80%, and the search for the genetic basis of
this disease has been frustrating. Because schizophrenia has no distinguishing pathology or …

Multiple research paradigms have provided evidence for a substantial genetic component in
the etiology of schizophrenic disorders. This article reviews the major research strategies …