Antimicrobial peptide magainin 2 forms pores in lipid membranes and induces membrane
permeation of the cellular contents. Although this permeation is likely the main cause of its …

The effect of membrane potential on plasma membrane damage generated by antimicrobial
peptides (AMPs) is an important, yet poorly characterized, process. Here, we studied the …

Using a flexibility prediction algorithm and in silico structural modeling, we have calculated
the intrinsic flexibility of several magainin derivatives. In the case of magainin-2 (Mag-2) and …

Conspectus Biological membranes separate the interior of cells or cellular compartments
from their outer environments. This barrier function of membranes can be disrupted by …

We investigated the interaction of the antimicrobial peptides Ala19-magainin 2 amide and
magainin 2 amide with lipid using two lipid photolabels, azidobenzoyl galactosylceramide …

The cationic antimicrobial peptides PGLa and magainin 2 (Mag2) are known for their
antimicrobial activity and synergistic enhancement in antimicrobial and membrane leakage …

The antimicrobial peptides magainin 2 and PGLa, discovered in the skin of the African
clawed frog, Xenopus laevis, exhibit marked synergism [Westerhoff, HV, Zasloff, M., Rosner …

Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …

Magainin 2 and PGLa are antimicrobial peptides found together in frog skin secretions.
When added as a mixture they show an order of magnitude increase in antibacterial activity …

The precise mode of the antimicrobial activity of Magainin (Mag)—an antimicrobial peptide
(AMP)—is still unclear. In this study, the conformation of Mag was characterized in water …