Artemisinin-based combination therapies (ACTs) are the best anti-malarial drugs available now. Artemisinin enhances efficacy and has the potential of lowering the rate at which …
2. Delayed parasite clearance does not necessarily lead to treatment failure. In the Greater Mekong subregion (GMS), high treatment failure rates following treatment with an ACT have …
RM Fairhurst, AM Dondorp - Microbiology spectrum, 2016 - Am Soc Microbiol
For more than five decades, Southeast Asia (SEA) has been fertile ground for the emergence of drug-resistant Plasmodium falciparum malaria. After generating parasites …
C Wongsrichanalai, CH Sibley - Clinical Microbiology and Infection, 2013 - Elsevier
Following a decade-long scale up of malaria control through vector control interventions, the introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination …
MF Boni - Frontiers in Epidemiology, 2022 - frontiersin.org
Treatment of symptomatic malaria became a routine component of the clinical and public health response to malaria after the second world war. However, all antimalarial drugs …
J Wang, C Xu, YK Wong, Y Li, F Liao, T Jiang, Y Tu - Engineering, 2019 - Elsevier
Artemisinin and its derivatives represent the most important and influential class of drugs in the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …
Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed in traditional Chinese medicine. Prof. You-you Tu discovered artemisinin in the 1960s, so …
L Von Seidlein, A Dondorp - Expert review of anti-infective therapy, 2015 - Taylor & Francis
The emergence and spread of antimalarial resistance has been a major liability for malaria control. The spread of chloroquine-resistant Plasmodium falciparum strains had catastrophic …
Application of traditional Chinese drug, artemisinin, originally derived from Artemisia annua L., in malaria therapy has now been globally accepted. Artemisinin and its derivatives, with …