Early parasitological response following artemisinin-containing regimens: a critical review of the literature

D Das, RN Price, D Bethell, PJ Guerin, K Stepniewska - Malaria journal, 2013 - Springer
Abstract Background Parasitaemia on Day 3 has been proposed as a useful alert of
potential artemisinin resistance, however, the normal variation of parasite clearance …

Artemisinin-based combination therapies (ACTs): best hope for malaria treatment but inaccessible to the needy!

TK Mutabingwa - Acta tropica, 2005 - Elsevier
Artemisinin-based combination therapies (ACTs) are the best anti-malarial drugs available
now. Artemisinin enhances efficacy and has the potential of lowering the rate at which …

[PDF][PDF] Artemisinin and artemisinin-based combination therapy resistance: status report

World Health Organization - 2016 - apps.who.int
2. Delayed parasite clearance does not necessarily lead to treatment failure. In the Greater
Mekong subregion (GMS), high treatment failure rates following treatment with an ACT have …

Artemisinin-Resistant Plasmodium falciparum Malaria

RM Fairhurst, AM Dondorp - Microbiology spectrum, 2016 - Am Soc Microbiol
For more than five decades, Southeast Asia (SEA) has been fertile ground for the
emergence of drug-resistant Plasmodium falciparum malaria. After generating parasites …

[HTML][HTML] Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance

C Wongsrichanalai, CH Sibley - Clinical Microbiology and Infection, 2013 - Elsevier
Following a decade-long scale up of malaria control through vector control interventions, the
introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination …

Breaking the cycle of malaria treatment failure

MF Boni - Frontiers in Epidemiology, 2022 - frontiersin.org
Treatment of symptomatic malaria became a routine component of the clinical and public
health response to malaria after the second world war. However, all antimalarial drugs …

[HTML][HTML] Artemisinin, the magic drug discovered from traditional Chinese medicine

J Wang, C Xu, YK Wong, Y Li, F Liao, T Jiang, Y Tu - Engineering, 2019 - Elsevier
Artemisinin and its derivatives represent the most important and influential class of drugs in
the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …

Discovery and development of artemisinin and related compounds

C Liu - Chinese Herbal Medicines, 2017 - Elsevier
Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed
in traditional Chinese medicine. Prof. You-you Tu discovered artemisinin in the 1960s, so …

Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance

L Von Seidlein, A Dondorp - Expert review of anti-infective therapy, 2015 - Taylor & Francis
The emergence and spread of antimalarial resistance has been a major liability for malaria
control. The spread of chloroquine-resistant Plasmodium falciparum strains had catastrophic …

Updates on artemisinin: an insight to mode of actions and strategies for enhanced global production

N Pandey, S Pandey-Rai - Protoplasma, 2016 - Springer
Application of traditional Chinese drug, artemisinin, originally derived from Artemisia annua
L., in malaria therapy has now been globally accepted. Artemisinin and its derivatives, with …