Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

TA Ajslev, CS Andersen, M Gamborg… - International journal of …, 2011 - nature.com
Objective: To investigate whether delivery mode (vaginal versus by caesarean section),
maternal pre-pregnancy body mass index (BMI) and early exposure to antibiotics (< 6 …

Antibiotic treatment during infancy and increased body mass index in boys: an international cross-sectional study

R Murphy, AW Stewart, I Braithwaite… - International journal of …, 2014 - nature.com
Objective: To investigate whether antibiotic exposure during the first year of life is associated
with increased childhood body mass index (BMI). Design: Secondary analysis from a multi …

Childhood BMI in relation to microbiota in infancy and lifetime antibiotic use

K Korpela, MAC Zijlmans, M Kuitunen, K Kukkonen… - Microbiome, 2017 - Springer
Background Children with high body mass index (BMI) at preschool age are at risk of
developing obesity. Early identification of factors that increase the risk of excessive weight …

[HTML][HTML] Effect of mother's weight on infant's microbiota acquisition, composition, and activity during early infancy: a prospective follow-up study initiated in early …

MC Collado, E Isolauri, K Laitinen… - The American journal of …, 2010 - Elsevier
Background: It has been reported that deviations in gut microbiota composition may
predispose toward obesity, and specific groups of commensal gut bacteria may harvest …

Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation

LW Chen, J Xu, SE Soh, IM Aris, MT Tint… - International journal of …, 2020 - nature.com
Background In animal studies early life antibiotic exposure causes metabolic abnormalities
including obesity through microbiota disruption, but evidence from human studies is scarce …

Antibiotic exposure in early life and childhood overweight and obesity: a systematic review and meta‐analysis

SH Rasmussen, S Shrestha… - Diabetes, Obesity …, 2018 - Wiley Online Library
We conducted a systematic review and meta‐analysis of observational studies investigating
the association between antibiotic exposure in infancy and risk of childhood overweight and …

Antibiotics, obesity and the link to microbes-what are we doing to our children?

O Turta, S Rautava - BMC medicine, 2016 - Springer
Background Childhood obesity and overweight are among the greatest health challenges in
the pediatric population. Obese individuals exhibit marked differences in the composition of …

Exploring the contribution of maternal antibiotics and breastfeeding to development of the infant microbiome and pediatric obesity

DJ Lemas, S Yee, N Cacho, D Miller, M Cardel… - Seminars in Fetal and …, 2016 - Elsevier
Pediatric obesity, a significant public health concern, has been associated with adult
premature mortality and the development of type 2 diabetes and cardiovascular disease …

The intestinal microbiota composition and weight development in children: the KOALA Birth Cohort Study

L Scheepers, J Penders, CA Mbakwa, C Thijs… - International journal of …, 2015 - nature.com
Objective: To investigate whether the intestinal microbiota composition in early infancy is
associated with subsequent weight development in children. Methods: Analyses were …

Fetal programming of overweight through the microbiome: boys are disproportionately affected

AL Kozyrskyj, R Kalu, PT Koleva… - Journal of developmental …, 2016 - cambridge.org
Maternal and childhood obesity in pregnancy are worrisome public health issues facing our
world today. New gene sequencing methods have advanced our knowledge of the …