An essential requisite for transmission of Plasmodium, the causative agent of malaria, is the
successful completion of a complex developmental cycle in its mosquito vector. Of hundreds …

An essential, but poorly understood part of malaria transmission by mosquitoes is the
development of the ookinetes into the sporozoite‐producing oocysts on the mosquito midgut …

Background Despite the importance of the Plasmodium berghei oocyst capsule protein
(PbCap380) in parasite survival, very little is known about the orthologous Plasmodium …

The sporozoite, the stage of the malaria parasite transmitted by the mosquito, first develops
for∼ 2 weeks in an oocyst. Rupture of the oocyst capsule is required for release of …

Understanding the life cycle of the malaria parasite in its mosquito vector is essential for
developing new strategies to combat this disease. Subtractive hybridization cDNA libraries …

Although the ability of mosquitoes to limit Plasmodium infection is well documented, many
questions remain as to how malaria parasites are recognized and killed by the mosquito …

Gonzalez-Ceron, L., Rodriguez, MH, Santillan, F., Chavez, B., Nettel, JA, Hernandez-Avila,
JE, and Kain, KC 2001. Plasmodium vivax: Ookinete destruction and oocyst development …

The sporozoite stage of the Plasmodium parasite is formed by budding from a multinucleate
oocyst in the mosquito midgut. During their life, sporozoites must infect the salivary glands of …

Mouse monoclonal antibody 13.1 (mAb 13.1) directed against Pbs21, a 21-kDa sexual-
stage surface protein of Plasmodium berghei, is known to inhibit oocyst development from …

Malaria parasites are less vulnerable to mosquito immune responses once ookinetes
transform into oocysts, facilitating parasite development in the mosquito. However, the …