Transmission of malaria parasites to the mosquito is mediated by sexual precursor cells, the
gametocytes. Upon entering the mosquito midgut, the gametocytes egress from the …

The Plasmodium liver forms are bridgehead stages between the mosquito sporozoite stages
and mammalian blood stages that instigate the malaria disease. In hepatocytes …

The malaria parasite Plasmodium has an absolute requirement for both a vertebrate and a
mosquito host in order to complete its life cycle, and its interactions with the latter provide the …

Our understanding of the intricate interactions between the malarial parasite and the
mosquito vector is complicated both by the number and diversity of parasite and vector …

Abstract The SAS6-like (SAS6L) protein, a truncated paralogue of the ubiquitous basal
body/centriole protein SAS6, has been characterised recently as a flagellum protein in …

Pore-forming proteins are employed by many pathogens to achieve successful host
colonization. Intracellular pathogens use pore-forming proteins to invade host cells, survive …

The transformation of malaria ookinetes into oocysts occurs in the mosquito midgut and is a
major bottleneck for parasite transmission. The secreted ookinete surface protein …

Plasmodium falciparum malaria remains a major cause of global morbidity and mortality,
mainly in sub-Saharan Africa. The numbers of new malaria cases and deaths have been …

We studied the point at which a monoclonal antibody (mAb C5) to a surface protein (Pgs25)
on Plasmodium gallinaceum ookinetes blocked the infection of Aedes aegypti mosquitoes …

The malarial parasite has two hosts in its life cycle, a vertebrate and a mosquito. We report
here that malarial invasion into these hosts is mediated by a protein, designated cell …