Safety and efficacy of the RTS, S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised …

KP Asante, S Abdulla, S Agnandji, J Lyimo… - The Lancet infectious …, 2011 - thelancet.com
Summary Background The RTS, S/AS01 E candidate malaria vaccine is being developed for
immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 …

RTS, S malaria vaccine pilots in three African countries

P Adepoju - The Lancet, 2019 - thelancet.com
World Malaria Day 2019 was marked by calls for urgent action to get the global response to
malaria back on track, but attention was predominantly centred around the RTS, S vaccine …

RTS, S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials

M Van den Berg, B Ogutu, NK Sewankambo… - Trials, 2019 - Springer
A malaria vaccine as part of the integrated malaria control and elimination efforts will have a
major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS, S, now …

[HTML][HTML] Increasing challenges of malaria control in sub-Saharan Africa: Priorities for public health research and policymakers

HJ Oladipo, YA Tajudeen, IO Oladunjoye… - Annals of Medicine and …, 2022 - Elsevier
The ever-increasing cases and mortality due to malaria remains one of the most important
public health threats, especially in sub-Saharan Africa—where this burden is considerably …

Malaria vaccines: a toy for travelers or a tool for eradication?

B Genton - Expert review of vaccines, 2008 - Taylor & Francis
The demonstration of efficacy of two candidate malaria vaccines in children living in malaria-
endemic areas, namely RTS, S from the circumsporozoite protein that reduced infection and …

Efficacy of RTS, S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 …

AM Samuels, D Ansong, SK Kariuki, S Adjei… - The Lancet Infectious …, 2022 - thelancet.com
Background Controlled infection studies in malaria-naive adults suggest increased vaccine
efficacy for fractional-dose versus full-dose regimens of RTS, S/AS01. We report first results …

Immunogenicity and safety of the RTS, S/AS01 malaria vaccine co-administered with measles, rubella and yellow fever vaccines in Ghanaian children: a phase IIIb …

KP Asante, D Ansong, S Kaali, S Adjei, M Lievens… - Vaccine, 2020 - Elsevier
Background To optimize vaccine implementation visits for young children, it could be
efficient to administer the first RTS, S/AS01 malaria vaccine dose during the Expanded …

[HTML][HTML] Cost-effectiveness and public health impact of RTS, S/AS01 E malaria vaccine in Malawi, using a Markov static model

L Ndeketa, D Mategula, DJ Terlouw… - Wellcome Open …, 2020 - ncbi.nlm.nih.gov
Background: The RTS, S/AS01 E malaria vaccine is being assessed in Malawi, Ghana and
Kenya as part of a large-scale pilot implementation programme. Even if impactful, its …

Four year immunogenicity of the RTS, S/AS02A malaria vaccine in Mozambican children during a phase IIb trial

P Aide, C Dobano, J Sacarlal, JJ Aponte… - Vaccine, 2011 - Elsevier
Previous studies with the malaria vaccine RTS, S/AS02A in young children in a malaria
endemic area of Mozambique have shown it to have a promising safety profile and to reduce …

Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2004 - thelancet.com
Background Development of an effective malaria vaccine could greatly contribute to disease
control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …