World Malaria Day 2019 was marked by calls for urgent action to get the global response to malaria back on track, but attention was predominantly centred around the RTS, S vaccine …
M Van den Berg, B Ogutu, NK Sewankambo… - Trials, 2019 - Springer
A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS, S, now …
The ever-increasing cases and mortality due to malaria remains one of the most important public health threats, especially in sub-Saharan Africa—where this burden is considerably …
B Genton - Expert review of vaccines, 2008 - Taylor & Francis
The demonstration of efficacy of two candidate malaria vaccines in children living in malaria- endemic areas, namely RTS, S from the circumsporozoite protein that reduced infection and …
AM Samuels, D Ansong, SK Kariuki, S Adjei… - The Lancet Infectious …, 2022 - thelancet.com
Background Controlled infection studies in malaria-naive adults suggest increased vaccine efficacy for fractional-dose versus full-dose regimens of RTS, S/AS01. We report first results …
KP Asante, D Ansong, S Kaali, S Adjei, M Lievens… - Vaccine, 2020 - Elsevier
Background To optimize vaccine implementation visits for young children, it could be efficient to administer the first RTS, S/AS01 malaria vaccine dose during the Expanded …
Background: The RTS, S/AS01 E malaria vaccine is being assessed in Malawi, Ghana and Kenya as part of a large-scale pilot implementation programme. Even if impactful, its …
Previous studies with the malaria vaccine RTS, S/AS02A in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce …
Background Development of an effective malaria vaccine could greatly contribute to disease control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …