Co-exposure to lead and high-fat diet aggravates systemic inflammation in mice by altering gut microbiota and the LPS/TLR4 pathway

N Wang, C Li, X Gao, Y Huo, Y Li, F Cheng… - Metallomics, 2024 - academic.oup.com
This study reports the toxicity of Pb exposure on systemic inflammation in high-fat-diet (HFD)
mice and the potential mechanisms. Results indicated that Pb exacerbated intestinal barrier …

Meat proteins in a high-fat diet have a substantial impact on intestinal barriers through mucus layer and tight junction protein suppression in C57BL/6J mice

M Hussain, MU Ijaz, MI Ahmad, IA Khan, SA Brohi… - Food & function, 2019 - pubs.rsc.org
Protein diets are well known for body maintenance and weight loss. However, it remains
unclear whether and how different protein sources affect the intestinal epithelial integrity …

[HTML][HTML] Nutritional protective mechanisms against gut inflammation

M Viladomiu, R Hontecillas, L Yuan, P Lu… - The Journal of nutritional …, 2013 - Elsevier
Inflammatory bowel disease (IBD) is a debilitating and widespread immune-mediated illness
characterized by excessive inflammatory and effector mucosal responses leading to tissue …

Supplemental antioxidants do not ameliorate colitis development in HLA-B27 transgenic rats despite extremely low glutathione levels in colonic mucosa

MAA Schepens, C Vink, AJ Schonewille… - Inflammatory Bowel …, 2011 - academic.oup.com
Background Oxidative stress is presumed to play an important role in inflammatory bowel
disease (IBD). Accordingly, antioxidant supplementation might be protective. Dietary calcium …

Bacillus amyloliquefaciens attenuates the intestinal permeability, oxidative stress and endoplasmic reticulum stress: transcriptome and microbiome analyses in …

J Yuan, H Meng, Y Liu, L Wang, Q Zhu… - Frontiers in …, 2024 - frontiersin.org
Endoplasmic reticulum (ER) stress is related to oxidative stress (OS) and leads to intestinal
injury. Bacillus amyloliquefaciens SC06 (SC06) can regulate OS, but its roles in intestinal …

[HTML][HTML] Novel Nutraceutical (silymarin, yeast β-glucan, prebiotics, and minerals) shifts gut microbiota and restores large intestine histology of diet-induced metabolic …

V Nehmi-Filho, JA de Freitas, LAM Franco… - Journal of Functional …, 2023 - Elsevier
Gut dysbiosis contributes to chronic inflammation and oxidative stress associated with
metabolic syndrome, and non-pharmacological, health-promoting supplements like …

Interactions between diet and the intestinal microbiota alter intestinal permeability and colitis severity in mice

SR Llewellyn, GJ Britton, EJ Contijoch, OH Vennaro… - Gastroenterology, 2018 - Elsevier
Background & Aims It is not clear how the complex interactions between diet and the
intestinal microbiota affect development of mucosal inflammation or inflammatory bowel …

Glyceryl butyrate attenuates enterotoxigenic Escherichia coli-induced intestinal inflammation in piglets by inhibiting the NF-κB/MAPK pathways and modulating the gut …

M Tian, L Li, Z Tian, H Zhao, F Chen, W Guan… - Food & Function, 2022 - pubs.rsc.org
The aims of this study were to evaluate whether a diet supplemented with glyceryl butyrate
could attenuate the immune-inflammatory response in piglets challenged with …

Alpha‐Ketoglutarate Attenuates Colitis in Mice by Increasing Lactobacillus Abundance and Regulating Stem Cell Proliferation via Wnt‐Hippo Signaling

X Si, H Jia, N Liu, J Li, L Pan, J Wang… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Inflammatory bowel disease is an inflammatory gastrointestinal disorder associated
with intestinal barrier damage, cell proliferation disorder, and dysbiosis of the intestinal …

Chickpea-supplemented diet alters the gut microbiome and enhances gut barrier integrity in C57Bl/6 male mice

JM Monk, D Lepp, W Wu, D Graf, LH McGillis… - Journal of Functional …, 2017 - Elsevier
Pulses are rich in fermentable fibre and phenolic compounds that have the potential to
modify baseline function within the gut microenvironment (microbiota and epithelial barrier) …