Artemisinin-based combination therapies (ACTs) have become the mainstay for malaria
treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent …

Artemisinin and its derivatives, in combination with partner drugs, are currently the most
effective treatments for malaria parasite infection. Even though artemisinin has been widely …

2. Delayed parasite clearance does not necessarily lead to treatment failure. In the Greater
Mekong subregion (GMS), high treatment failure rates following treatment with an ACT have …

The emergence of artemisinin resistance is a major obstacle to the global malaria
eradication/elimination programs. Artemisinin is a very fast-acting antimalarial drug and is …

Antimalarial drug therapies containing artemisinins,'ACTs', have become the mainstay for
treating uncomplicated malaria in endemic countries. This is a major public health …

Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium
falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the …

As drug-resistant falciparum malaria has continued to evolve and spread worldwide,
artemisinin-based combination therapies (ACT) have become the centerpiece of global …

Plasmodium falciparum resistance to chloroquine and sulphadoxine–pyrimethamine has led
to the recent adoption of artemisinin-based combination therapies (ACTs) as the first line of …

The artemisinins are the most effective antimalarial drugs known. They possess a
remarkably wide therapeutic index. These agents have been used in traditional Chinese …

The molecular pharmacology of artemisinin (ART)-based antimalarial drugs is incompletely
understood. Clinically, these drugs are used in combination with longer lasting partner drugs …