P852 A metabolomics approach to discover biomarkers of chronic intestinal inflammation associated with gut microbiota dysbiosis in ulcerative colitis and Celiac …

S Sitkin, T Vakhitov, E Tkachenko… - Journal of Crohn's …, 2018 - academic.oup.com
Background The effect of gut microbiota dysbiosis on human metabolome and the potential
of microbial and endogenous metabolites as biomarkers of chronic intestinal inflammation …

Colonization Resistance of the Gut Microbiota against Clostridium difficile

AE Pérez-Cobas, A Moya, MJ Gosalbes, A Latorre - Antibiotics, 2015 - mdpi.com
Antibiotics strongly disrupt the human gut microbiota, which in consequence loses its
colonization resistance capacity, allowing infection by opportunistic pathogens such as …

Epidemiology, Diagnosis, and Management of Clostridium difficile Infection in Patients with Inflammatory Bowel Disease

K Rao, PDR Higgins - Inflammatory bowel diseases, 2016 - academic.oup.com
Clostridium difficile infection (CDI) is a major source of morbidity and mortality for the US
health care system and frequently complicates the course of inflammatory bowel disease …

Microbial composition analysis of Clostridium difficile infections in an ulcerative colitis patient treated with multiple fecal microbiota transplantations

C Brace, GB Gloor, M Ropeleski… - Journal of Crohn's …, 2014 - academic.oup.com
Fecal microbiota transplantation (FMT) is a promising therapy for Clostridium difficile
infection (CDI). However, questions remain regarding efficacy and safety in inflammatory …

Fecal microbiota-based therapeutics for recurrent Clostridium difficile infection, ulcerative colitis and obesity

C Carlucci, EO Petrof, E Allen-Vercoe - EBioMedicine, 2016 - thelancet.com
The human gut microbiome is a complex ecosystem of fundamental importance to human
health. Our increased understanding of gut microbial composition and functional interactions …

Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile

MA Engevik, KA Engevik… - American Journal …, 2015 - journals.physiology.org
Clostridium difficile infection (CDI) is principally responsible for hospital acquired, antibiotic-
induced diarrhea and colitis and represents a significant financial burden on our healthcare …

Effects of defined gut microbial ecosystem components on virulence determinants of Clostridioides difficile

C Carlucci, CS Jones, K Oliphant, S Yen… - Scientific reports, 2019 - nature.com
Many cases of Clostridioides difficile infection (CDI) are poorly responsive to standard
antibiotic treatment strategies, and often patients suffer from recurrent infections …

Host sorbitol and bacterial sorbitol utilization promote Clostridioides difficile infection in inflammatory bowel disease

Z Yang, J Qin, L Zhao, T Chen, Q Huang, Y Jian… - Gastroenterology, 2023 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) is a widespread gastrointestinal
inflammatory disorder with globally increasing incidence. Clostridioides difficile infection …

Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case–control study in India

J Kabeerdoss, V Sankaran, S Pugazhendhi… - BMC …, 2013 - Springer
Background Alterations in the fecal bacterial flora occur in inflammatory bowel disease
(IBD). We examined the abundance and diversity of Clostridium leptum group, an important …

[HTML][HTML] Update on gut microbiota in gastrointestinal diseases

A Nishida, K Nishino, M Ohno, K Sakai… - World Journal of …, 2022 - ncbi.nlm.nih.gov
The human gut is a complex microbial ecosystem comprising approximately 100 trillion
microbes collectively known as the “gut microbiota”. At a rough estimate, the human gut …