The potential use of the CRISPR‐Cas system for HIV‐1 gene therapy
GDN Sanches-da-Silva, LFS Medeiros… - International journal of …, 2019 - Wiley Online Library
The HIV‐1 virus (human immunodeficiency virus) affects 36.9 million people worldwide, with
approximately 900000 deaths in 2017. The virus carrier can develop severe …
approximately 900000 deaths in 2017. The virus carrier can develop severe …
A CRISPR-Cas Cure for HIV/AIDS
M Hussein, MA Molina, B Berkhout… - International journal of …, 2023 - mdpi.com
Human immunodeficiency virus (HIV) infections and HIV-induced acquired
immunodeficiency syndrome (AIDS) continue to represent a global health burden. There is …
immunodeficiency syndrome (AIDS) continue to represent a global health burden. There is …
Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS
Z Huang, A Tomitaka, A Raymond, M Nair - Gene therapy, 2017 - nature.com
Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) remains
a major health hazard despite significant advances in prevention and treatment of HIV …
a major health hazard despite significant advances in prevention and treatment of HIV …
CRISPR/Cas9: a tool to eradicate HIV-1
R Bhowmik, B Chaubey - AIDS Research and Therapy, 2022 - Springer
The development of antiretroviral therapy (ART) has been effective in suppressing HIV
replication. However, severe drug toxicities due to the therapy and its failure in targeting the …
replication. However, severe drug toxicities due to the therapy and its failure in targeting the …
The therapeutic application of CRISPR/Cas9 technologies for HIV
Introduction: The use of antiretroviral therapy has led to a significant decrease in morbidity
and mortality in HIV-infected individuals. Nevertheless, gene-based therapies represent a …
and mortality in HIV-infected individuals. Nevertheless, gene-based therapies represent a …
Application of CRISPR/Cas9-based gene editing in HIV-1/AIDS therapy
Q Xiao, D Guo, S Chen - Frontiers in cellular and infection …, 2019 - frontiersin.org
Despite the fact that great efforts have been made in the prevention and therapy of HIV-1
infection, HIV-1/AIDS remains a major threat to global human health. Highly active …
infection, HIV-1/AIDS remains a major threat to global human health. Highly active …
Pathways Toward a Functional HIV-1 Cure: Balancing Promise and Perils of CRISPR Therapy
First identified as a viral defense mechanism, clustered regularly interspaced short
palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) has been …
palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) has been …
Developmental progress of CRISPR/Cas9 and its therapeutic applications for HIV‐1 infection
Q Deng, Z Chen, L Shi, H Lin - Reviews in Medical Virology, 2018 - Wiley Online Library
The CRISPR/Cas9 system has been developed as a powerful tool for targeted gene editing.
As a result of technical enhancements in recent years, this technology has become the …
As a result of technical enhancements in recent years, this technology has become the …
Crispr-cas replacing antiviral drugs against hiv: An update
Various antiretroviral drugs do not kill or cure the human immunodeficiency virus (HIV) but
do prevent the replication of the virus. The combination of antiretroviral drugs is known as …
do prevent the replication of the virus. The combination of antiretroviral drugs is known as …
Application progress of CRISPR/Cas9 genome editing technology in the treatment of HIV-1 infection
Y Han, QW Li - Yi Chuan= Hereditas, 2016 - europepmc.org
The goal of gene therapy is to introduce foreign genes into human target cells in a certain
way to correct or compensate diseases caused by defective or abnormal genes. Therefore …
way to correct or compensate diseases caused by defective or abnormal genes. Therefore …