Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)- infected mosquitoes with a present scale of symptoms ranging from moderate fever to …
N Arora, LC Anbalagan, AK Pannu - Risk Management and …, 2021 - Taylor & Francis
Background Recent advances in mosquito eradication and antimalarial treatments have reduced the malaria burden only modestly. An effective malaria vaccine remains a high …
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …
AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half of the world population is still exposed to the risk of contracting malaria. Developing an …
JA Regules, JF Cummings… - Expert review of …, 2011 - Taylor & Francis
Malaria continues to be a worldwide leading cause of morbidity and mortality, and the development of an effective malaria vaccine remains a research imperative. Of the multiple …
RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
Background An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS, S/AS01 is being conducted in seven African countries …
RTS, S is the most advanced candidate vaccine against human malaria. During its remarkable journey from conception and design in the early 1980s to the multicenter Phase …
J Sacarlal, P Aide, JJ Aponte, M Renom… - Journal of Infectious …, 2009 - academic.oup.com
Background We previously reported that the RTS, S/AS02A vaccine had an acceptable safety profile, was immunogenic, and demonstrated efficacy against Plasmodium falciparum …
JG Beeson, L Kurtovic, C Valim, KP Asante… - Science Translational …, 2022 - science.org
The RTS, S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of …