Intracellular antioxidants dissolve man-made antioxidant nanoparticles: using redox vulnerability of nanoceria to develop a responsive drug delivery system

F Muhammad, A Wang, W Qi, S Zhang… - ACS applied materials & …, 2014 - ACS Publications
Regeneratable antioxidant property of nanoceria has widely been explored to minimize the
deleterious influences of reactive oxygen species. Limited information is, however, available …

Central nervous system injury meets nanoceria: opportunities and challenges

W Yang, M Zhang, J He, M Gong, J Sun… - Regenerative …, 2022 - academic.oup.com
Central nervous system (CNS) injury, induced by ischemic/hemorrhagic or traumatic
damage, is one of the most common causes of death and long-term disability worldwide …

[HTML][HTML] Ceria nanoparticle theranostics: Harnessing antioxidant properties in biomedicine and beyond

S Banavar, A Deshpande, S Sur… - Journal of Physics …, 2021 - iopscience.iop.org
Theranostic nanoparticles (NPs) which provide both therapeutic and diagnostic capabilities
have potential to fundamentally change biomedical sciences and improve disease …

Treatment of neurodegenerative disorders with radical nanomedicine

N Singh, CA Cohen… - Annals of the New York …, 2007 - Wiley Online Library
In engineering and materials science, nanotechnology has provided many advances that
effectively reduce oxidative damage generated by free radical production. Despite such …

Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats

RA Yokel, TC Au, R MacPhail, SS Hardas… - Toxicological …, 2012 - academic.oup.com
Nanoceria is used as a catalyst in diesel fuel, as an abrasive in printed circuit manufacture,
and is being pursued as an antioxidant therapeutic. Our objective is to extend previous …

Ce3+ Ions Determine Redox-Dependent Anti-apoptotic Effect of Cerium Oxide Nanoparticles

I Celardo, M De Nicola, C Mandoli, JZ Pedersen… - ACS …, 2011 - ACS Publications
Antioxidant therapy is the novel frontier to prevent and treat an impressive series of severe
human diseases, and the search for adequate antioxidant drugs is fervent. Cerium oxide …

Rat hippocampal responses up to 90 days after a single nanoceria dose extends a hierarchical oxidative stress model for nanoparticle toxicity

SS Hardas, R Sultana, G Warrier, M Dan, P Wu… - …, 2014 - Taylor & Francis
Ceria engineered nanomaterials (ENMs) have very promising commercial and therapeutic
applications. Few reports address the effects of nanoceria in intact mammals, let alone long …

Simulated biological fluid exposure changes nanoceria's surface properties but not its biological response

RA Yokel, ML Hancock, B Cherian, AJ Brooks… - European Journal of …, 2019 - Elsevier
Nanoscale cerium dioxide (nanoceria) has industrial applications, capitalizing on its
catalytic, abrasive, and energy storage properties. It auto-catalytically cycles between Ce 3+ …

Cerium oxide nanoparticles stimulate proliferation of primary mouse embryonic fibroblasts in vitro

AL Popov, NR Popova, II Selezneva, AY Akkizov… - Materials Science and …, 2016 - Elsevier
The increasing application of cell therapy technologies in the treatment of various diseases
requires the development of new effective methods for culturing primary cells. The major …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …