Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition characterized
by impaired social interaction, compromised communication, and restrictive or stereotyped …

Eight-month old WAG/Rij rats, which developed spontaneous occurring absence seizures,
showed a reduced function of mGlu1 metabotropic glutamate receptors in the thalamus, as …

Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …

It is well established that prenatal valproic acid exposure in rats leads to autism-like
behaviours and social deficits. Long-term potentiation changes in the brain have been …

Autism is a heterogeneous, behaviorally defined developmental disorder with unknown
etiology but thought to be the result of environmental insult acting upon the developing brain …

Glutamate is the major excitatory neurotransmitter in the brain. The glutamate system plays
an important role in the formation of synapses during brain development and synaptic …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …

The disorders of the glutamatergic neurotransmission have been associated with
pathogenesis of autism. In this study we evaluated the impact of the in vivo and ex vivo test …

High doses of mGluR5 antagonists have anticonvulsant effects in multiple seizure models in
both adult and immature animals. Data on potential behavioral effects in immature animals …

Interactions between subtypes of dopamine, glutamate and adenosine receptors seem to
play an important integrative role in the function of striatal gamma-aminobutyric acid (GABA) …