CDKL5 (cyclin-dependent kinase-like 5) deficiency disorder (CDD) is a severe
neurodevelopmental disease that mostly affects girls, who are heterozygous for mutations in …

CDKL5 disorder is a devastating neurodevelopmental disorder associated with epilepsy,
developmental retardation, autism, and related phenotypes. Mutations in the CDKL5 gene …

Mutations in the Cyclin-dependent kinase-like 5 (CDKL5) gene cause severe
neurodevelopmental disorders. Recently we have generated Cdkl5 KO mice by targeting …

Mutations in the X-linked CDKL5 (cyclin-dependent kinase-like 5) gene have been
associated with several forms of neurodevelopmental disorders, including atypical Rett …

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been identified
in a neurodevelopmental disorder characterized by early-onset intractable seizures, severe …

Abstract Cyclin-dependent kinase like-5 (CDKL5) disorder is a rare neurodevelopmental
disease caused by mutations in the CDKL5 gene. The consequent misexpression of the …

CDKL5 deficiency disorder (CDD) is a complex clinical condition resulting from non-
functional or absent CDKL5 protein, a serine–threonine kinase pivotal for neural maturation …

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene are responsible for
the onset of CDKL5 Deficiency Disorder (CDD), a neurological pathology characterised by …

Abstract Cyclin-dependent kinase-like 5 (CDKL5) is a gene encoding a serine/threonine
kinase that possesses an N-terminal catalytic domain and a large C-terminal domain and is …

Abstract Cyclin-dependent kinase-like 5 (Cdkl5) deficiency disorder (CDD) is a severe
neurodevelopmental condition caused by mutations in the X-linked Cdkl5 gene. CDD is …