Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting

A Franzone, E McFadden, S Leonardi, R Piccolo… - Journal of the American …, 2019 - jacc.org
Abstract Background: The GLOBAL LEADERS (GLOBAL LEADERS: A Clinical Study
Comparing Two Forms of Anti-platelet Therapy After Stent Implantation) study randomly …

Ticagrelor with aspirin or alone in high-risk patients after coronary intervention: rationale and design of the TWILIGHT study

U Baber, G Dangas, DJ Cohen, CM Gibson… - American heart …, 2016 - Elsevier
Background Dual antiplatelet therapy (DAPT) is necessary to prevent thrombosis yet
increases bleeding after percutaneous coronary intervention (PCI) with drug-eluting stents …

Impact of long-term ticagrelor monotherapy following 1-month dual antiplatelet therapy in patients who underwent complex percutaneous coronary intervention …

PW Serruys, K Takahashi, P Chichareon… - European heart …, 2019 - academic.oup.com
Aims To evaluate the impact of an experimental strategy [23-month ticagrelor monotherapy
following 1-month dual antiplatelet therapy (DAPT)] vs. a reference regimen (12-month …

Ticagrelor monotherapy versus dual-antiplatelet therapy after PCI: an individual patient-level meta-analysis

M Valgimigli, R Mehran, A Franzone… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to compare ticagrelor monotherapy with dual-
antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with drug-eluting …

Ticagrelor monotherapy versus aspirin monotherapy at 12 months after percutaneous coronary intervention: a landmark analysis of the GLOBAL LEADERS trial

M Ono, H Hara, H Kawashima, C Gao, R Wang… - …, 2022 - research.rug.nl
Background: The optimal antiplatelet strategy in the second year after percutaneous
coronary intervention (PCI) remains unclear. Aims: We aimed to compare ticagrelor …

Ticagrelor or clopidogrel monotherapy vs dual antiplatelet therapy after percutaneous coronary intervention: a systematic review and patient-level meta-analysis

M Valgimigli, F Gragnano, M Branca… - JAMA …, 2024 - jamanetwork.com
Importance Among patients undergoing percutaneous coronary intervention (PCI), it
remains unclear whether the treatment efficacy of P2Y 12 inhibitor monotherapy after a short …

Long-term ticagrelor for secondary prevention in patients with prior myocardial infarction and no history of coronary stenting: insights from PEGASUS-TIMI 54

RHM Furtado, JC Nicolau, G Magnani, K Im… - European heart …, 2020 - academic.oup.com
Aims PEGASUS-TIMI 54 demonstrated that long-term dual antiplatelet therapy (DAPT) with
aspirin and ticagrelor reduced the risk of major adverse cardiovascular events (MACE), with …

Ticagrelor with or without aspirin after complex PCI

G Dangas, U Baber, S Sharma, G Giustino… - Journal of the American …, 2020 - jacc.org
Background Whether a regimen of ticagrelor monotherapy attenuates bleeding
complications without increasing ischemic risk in patients undergoing complex …

Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome: the TICO …

BK Kim, SJ Hong, YH Cho, KH Yun, YH Kim, Y Suh… - Jama, 2020 - jamanetwork.com
Importance Discontinuing aspirin after short-term dual antiplatelet therapy (DAPT) was
evaluated as a bleeding reduction strategy. However, the strategy of ticagrelor monotherapy …

Efficacy and safety of ticagrelor monotherapy by clinical presentation: pre‐specified analysis of the GLOBAL LEADERS Trial

P Vranckx, M Valgimigli, A Odutayo… - Journal of the …, 2021 - Am Heart Assoc
Background The optimal duration of dual antiplatelet therapy after coronary drug‐eluting
stent placement in adults with stable coronary artery disease (SCAD) versus acute coronary …