Prasugrel-based de-escalation of dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (HOST-REDUCE …

HS Kim, J Kang, D Hwang, JK Han, HM Yang, HJ Kang… - The Lancet, 2020 - thelancet.com
Summary Background A potent P2Y12 inhibitor-based dual antiplatelet therapy is
recommended for up to 1 year in patients with acute coronary syndrome receiving …

Guided and unguided de-escalation from potent P2Y12 inhibitors among patients with acute coronary syndrome: a meta-analysis

AH Tavenier, R Mehran, M Chiarito… - European Heart …, 2022 - academic.oup.com
Aim Optimal dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary
intervention (PCI) for acute coronary syndrome (ACS) intends to balance ischemic and …

Dual antiplatelet therapy de-escalation in acute coronary syndrome: an individual patient meta-analysis

J Kang, KD Rizas, KW Park, J Chung… - European Heart …, 2023 - academic.oup.com
Aims Dual-antiplatelet therapy (DAPT) with aspirin and a potent P2Y12 inhibitor is the
standard treatment for patients with acute coronary syndrome (ACS) undergoing …

Benefit of switching dual antiplatelet therapy after acute coronary syndrome: the TOPIC (timing of platelet inhibition after acute coronary syndrome) randomized study

T Cuisset, P Deharo, J Quilici, TW Johnson… - European heart …, 2017 - academic.oup.com
Abstract Aims Newer P2Y12 blockers (prasugrel and ticagrelor) demonstrated significant
ischaemic benefit over clopidogrel after acute coronary syndrome (ACS). However, both …

[HTML][HTML] Prasugrel versus clopidogrel in patients with acute coronary syndromes

SD Wiviott, E Braunwald, CH McCabe… - … England Journal of …, 2007 - Mass Medical Soc
Background Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of
treatment to prevent thrombotic complications of acute coronary syndromes and …

Oral antiplatelet therapy after acute coronary syndrome: a review

H Kamran, H Jneid, WT Kayani, SS Virani, GN Levine… - Jama, 2021 - jamanetwork.com
Importance Acute coronary syndrome (ACS) is a major cause of morbidity and mortality in
the United States with an annual incidence of approximately 1 million. Dual antiplatelet …

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Pre-treatment with P2Y12 inhibitors in ACS patients: who, when, why, and which agent?

D Sibbing, A Kastrati, PB Berger - European heart journal, 2016 - academic.oup.com
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the mainstay
of treatment for acute coronary syndrome (ACS) patients, whether they undergo a …

De-escalation of dual antiplatelet therapy in patients with acute coronary syndromes

S Shoji, T Kuno, T Fujisaki, H Takagi… - Journal of the American …, 2021 - jacc.org
Background Balancing the effects of dual antiplatelet therapy (DAPT) in the era of potent
P2Y12 inhibitors has become a cornerstone of acute coronary syndrome (ACS) …

6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a …

JY Hahn, YB Song, JH Oh, DK Cho, JB Lee, JH Doh… - The Lancet, 2018 - thelancet.com
Background Current guidelines recommend dual antiplatelet therapy (DAPT) of aspirin plus
a P2Y12 inhibitor for at least 12 months after implantation of drug-eluting stents (DES) in …