Characterization of crAss-like phage isolates highlights Crassvirales genetic heterogeneity and worldwide distribution

MD Ramos-Barbero, C Gómez-Gómez… - Nature …, 2023 - nature.com
Crassvirales (crAss-like phages) are an abundant group of human gut-specific
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …

Biology and taxonomy of crAss-like bacteriophages, the most abundant virus in the human gut

E Guerin, A Shkoporov, SR Stockdale, AG Clooney… - Cell host & …, 2018 - cell.com
CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of
available genome sequences for comparison has kept them enigmatic. Recently, sequence …

Discovery, diversity, and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts

A Gulyaeva, S Garmaeva, RAAA Ruigrok, D Wang… - Cell reports, 2022 - cell.com
The crAss-like phages are a diverse group of related viruses that includes some of the most
abundant viruses of the human gut. To explore their diversity and functional role in human …

ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis

AN Shkoporov, EV Khokhlova, CB Fitzgerald… - Nature …, 2018 - nature.com
CrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to
infect bacteria of the order Bacteroidales. Despite being found in~ 50% of individuals and …

Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features

N Yutin, S Benler, SA Shmakov, YI Wolf… - Nature …, 2021 - nature.com
CrAssphage is the most abundant human-associated virus and the founding member of a
large group of bacteriophages, discovered in animal-associated and environmental …

The crAss-like phage group: how metagenomics reshaped the human virome

EV Koonin, N Yutin - Trends in Microbiology, 2020 - cell.com
Metagenomics is currently the primary means for identifying new viruses. One of the most
impactful metagenomic discoveries is that of crAssphage, the most abundant human …

Isolation and characterisation of ΦcrAss002, a crAss-like phage from the human gut that infects Bacteroides xylanisolvens

E Guerin, AN Shkoporov, SR Stockdale, JC Comas… - Microbiome, 2021 - Springer
Background The gut phageome comprises a complex phage community of thousands of
individual strains, with a few highly abundant bacteriophages. CrAss-like phages, which …

Biogeographic study of human gut-associated crAssphage suggests impacts from industrialization and recent expansion

TP Honap, K Sankaranarayanan, SL Schnorr… - PLoS …, 2020 - journals.plos.org
CrAssphage (cross-assembly phage) is a bacteriophage that was first discovered in human
gut metagenomic data. CrAssphage belongs to a diverse family of crAss-like bacteriophages …

Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages

BA Siranosian, FB Tamburini, G Sherlock… - Nature …, 2020 - nature.com
CrAss-like phages are double-stranded DNA viruses that are prevalent in human gut
microbiomes. Here, we analyze gut metagenomic data from mother-infant pairs and patients …

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

RA Edwards, AA Vega, HM Norman, M Ohaeri… - Nature …, 2019 - nature.com
Microbiomes are vast communities of microorganisms and viruses that populate all natural
ecosystems. Viruses have been considered to be the most variable component of …