CRISPR analysis suggests that small circular single-stranded DNA smacoviruses infect Archaea instead of humans

C Díez-Villaseñor, F Rodriguez-Valera - Nature Communications, 2019 - nature.com
Smacoviridae is a family of small (~ 2.5 Kb) CRESS-DNA (Circular Rep Encoding Single-
Stranded (ss) DNA) viruses. These viruses have been found in faeces, were thought to infect …

Shining light on human gut bacteriophages

E Guerin, C Hill - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The human gut is a complex environment that contains a multitude of microorganisms that
are collectively termed the microbiome. Multiple factors have a role to play in driving the …

Long-read metagenomic exploration of extrachromosomal mobile genetic elements in the human gut

Y Suzuki, S Nishijima, Y Furuta, J Yoshimura, W Suda… - Microbiome, 2019 - Springer
Background Elucidating the ecological and biological identity of extrachromosomal mobile
genetic elements (eMGEs), such as plasmids and bacteriophages, in the human gut remains …

Still Something to Discover: Novel Insights into Escherichia coli Phage Diversity and Taxonomy

IHE Korf, JP Meier-Kolthoff, EM Adriaenssens… - Viruses, 2019 - mdpi.com
The aim of this study was to gain further insight into the diversity of Escherichia coli phages
followed by enhanced work on taxonomic issues in that field. Therefore, we present the …

Crass: identification and reconstruction of CRISPR from unassembled metagenomic data

CT Skennerton, M Imelfort, GW Tyson - Nucleic acids research, 2013 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR) constitute a bacterial
and archaeal adaptive immune system that protect against bacteriophage (phage). Analysis …

Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19

MF Neurath, K Überla, SC Ng - Gut, 2021 - gut.bmj.com
The gut microbiota is composed of bacteria, fungi and viruses. 1–3 While the presence and
composition of the bacteriome have been extensively studied in recent years, the 'dark …

The genomic landscape of reference genomes of cultivated human gut bacteria

X Lin, T Hu, J Chen, H Liang, J Zhou, Z Wu… - Nature …, 2023 - nature.com
Culture-independent metagenomic studies have revolutionized our understanding of the gut
microbiota. However, the lack of full genomes from cultured species is still a limitation for in …

Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection

CE Edwards, BL Yount, RL Graham… - Proceedings of the …, 2020 - National Acad Sciences
Zoonotic coronaviruses represent an ongoing threat, yet the myriads of circulating animal
viruses complicate the identification of higher-risk isolates that threaten human health …

Gut virome analysis of Cameroonians reveals high diversity of enteric viruses, including potential interspecies transmitted viruses

CK Yinda, E Vanhulle, N Conceição-Neto, L Beller… - MSphere, 2019 - Am Soc Microbiol
Diarrhea remains one of the most common causes of deaths in children. A limited number of
studies have investigated the prevalence of enteric pathogens in Cameroon, and as in many …

Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera

BG Blasdel, A Chevallereau, M Monot… - The ISME …, 2017 - academic.oup.com
Although the evolution of tailed bacteriophages has increasingly been better understood
through comparisons of their DNA sequences, the functional consequences of this evolution …