De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Tailoring oral antiplatelet therapy in acute coronary syndromes: from guidelines to clinical practice

S De Servi, A Landi, S Savonitto… - Journal of …, 2023 - journals.lww.com
The assessment of bleeding and ischemic risk is a crucial step in establishing appropriate
composition and duration of dual antiplatelet therapy (DAPT) in patients with acute coronary …

[HTML][HTML] De-escalation of antiplatelet therapy in patients with coronary artery disease: time to change our strategy?

P Sabouret, L Spadafora, D Fischman, W Ullah… - European Journal of …, 2023 - Elsevier
Dual antiplatelet therapy (DAPT) is the gold standard after acute coronary syndromes (ACS)
or chronic coronary syndromes (CCS) undergoing percutaneous coronary intervention …

Antithrombotic strategy for patients with acute coronary syndrome: a perspective from East Asia

Y Numasawa, M Sawano, R Fukuoka, K Ejiri… - Journal of Clinical …, 2020 - mdpi.com
Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention has become the
standard of care, particularly in patients with acute coronary syndrome (ACS). Current …

De-escalation of dual antiplatelet therapy in patients with acute coronary syndromes

S Shoji, T Kuno, T Fujisaki, H Takagi… - Journal of the American …, 2021 - jacc.org
Background Balancing the effects of dual antiplatelet therapy (DAPT) in the era of potent
P2Y12 inhibitors has become a cornerstone of acute coronary syndrome (ACS) …

Benefit of switching dual antiplatelet therapy after acute coronary syndrome: the TOPIC (timing of platelet inhibition after acute coronary syndrome) randomized study

T Cuisset, P Deharo, J Quilici, TW Johnson… - European heart …, 2017 - academic.oup.com
Abstract Aims Newer P2Y12 blockers (prasugrel and ticagrelor) demonstrated significant
ischaemic benefit over clopidogrel after acute coronary syndrome (ACS). However, both …

Shortening the duration of dual antiplatelet therapy after percutaneous coronary intervention for acute coronary syndrome: A systematic review and meta-analysis

DY Park, P Wang, S An, AA Grimshaw, J Frampton… - American heart …, 2022 - Elsevier
Introduction The decision to shorten the duration of DAPT following PCI in patients with ACS
remains controversial because of the concern for increased ischemic events. Methods We …

Predicting the risk of bleeding during dual antiplatelet therapy after acute coronary syndromes

J Alfredsson, B Neely, ML Neely, DL Bhatt… - Heart, 2017 - heart.bmj.com
Objectives Dual antiplatelet therapy (DAPT) with aspirin+ a P2Y12 inhibitor is recommended
for at least 12 months for patients with acute coronary syndrome (ACS), with shorter …

Short duration of DAPT versus de-escalation after percutaneous coronary intervention for acute coronary syndromes

C Laudani, A Greco, G Occhipinti, S Ingala… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to compare short dual antiplatelet therapy (DAPT) and
de-escalation in a network meta-analysis using standard DAPT as common comparator …

Acute coronary syndrome, antiplatelet therapy, and bleeding: a clinical perspective

G Tersalvi, L Biasco, GM Cioffi… - Journal of clinical medicine, 2020 - mdpi.com
Inhibition of platelet function by means of dual antiplatelet therapy (DAPT) is the cornerstone
of treatment of acute coronary syndrome (ACS). While preventing ischemic recurrences …