[HTML][HTML] Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows

T Van Den Bossche, BJ Kunath, K Schallert… - Nature …, 2021 - nature.com
Metaproteomics has matured into a powerful tool to assess functional interactions in
microbial communities. While many metaproteomic workflows are available, the impact of …

Perspective and guidelines for metaproteomics in microbiome studies

X Zhang, D Figeys - Journal of proteome research, 2019 - ACS Publications
The microbiome is emerging as a prominent factor affecting human health, and its dysbiosis
is associated with various diseases. Compositional profiling of microbiome is increasingly …

[HTML][HTML] A straightforward and efficient analytical pipeline for metaproteome characterization

A Tanca, A Palomba, S Pisanu, M Deligios… - Microbiome, 2014 - Springer
Background The massive characterization of host-associated and environmental microbial
communities has represented a real breakthrough in the life sciences in the last years. In this …

Data-independent acquisition mass spectrometry in metaproteomics of gut microbiota—implementation and computational analysis

J Aakko, S Pietila, T Suomi… - Journal of proteome …, 2019 - ACS Publications
Metagenomic approaches focus on taxonomy or gene annotation but lack power in defining
functionality of gut microbiota. Therefore, metaproteomics approaches have been introduced …

Assessing the impact of protein extraction methods for human gut metaproteomics

X Zhang, L Li, J Mayne, Z Ning, A Stintzi, D Figeys - Journal of proteomics, 2018 - Elsevier
Metaproteomics is a promising methodology for the functional characterizations of the gut
microbiome. However, the performance of metaproteomic analysis is affected by protein …

Enhancing metaproteomics—the value of models and defined environmental microbial systems

FA Herbst, V Lünsmann, H Kjeldal, N Jehmlich… - …, 2016 - Wiley Online Library
Metaproteomics—the large‐scale characterization of the entire protein complement of
environmental microbiota at a given point in time—has provided new features to study …

[HTML][HTML] Metaproteomics as a complementary approach to gut microbiota in health and disease

BA Petriz, OL Franco - Frontiers in chemistry, 2017 - frontiersin.org
Classic studies on phylotype profiling are limited to the identification of microbial
constituents, where information is lacking about the molecular interaction of these bacterial …

[HTML][HTML] Database-independent de novo metaproteomics of complex microbial communities

HBC Kleikamp, M Pronk, C Tugui, LG da Silva… - Cell Systems, 2021 - cell.com
Metaproteomics has emerged as one of the most promising approaches for determining the
composition and metabolic functions of complete microbial communities. Conventional …

Metaproteomic data analysis at a glance: advances in computational microbial community proteomics

T Muth, BY Renard, L Martens - Expert review of proteomics, 2016 - Taylor & Francis
Introduction: Within the last decade, the study of microbial communities has gained
increasing research interest also driven by the recognition of the important role of these …

[HTML][HTML] More is not always better: evaluation of 1D and 2D-LC-MS/MS methods for metaproteomics

T Hinzke, A Kouris, RA Hughes, M Strous… - Frontiers in …, 2019 - frontiersin.org
Metaproteomics, the study of protein expression in microbial communities, is a versatile tool
for environmental microbiology. Achieving sufficiently high metaproteome coverage to …