A meta-proteogenomic approach to peptide identification incorporating assembly uncertainty and genomic variation

S Li, H Tang, Y Ye - Molecular & Cellular Proteomics, 2019 - ASBMB
Matching metagenomic and/or metatranscriptomic data, currently often under-used, can be
useful reference for metaproteomic tandem mass spectra (MS/MS) data analysis. Here we …

Deep metaproteomics approach for the study of human microbiomes

X Zhang, W Chen, Z Ning, J Mayne, D Mack… - Analytical …, 2017 - ACS Publications
Host–microbiome interactions have been shown to play important roles in human health and
diseases. Most of the current studies of the microbiome have been performed by genomic …

[HTML][HTML] Challenges and perspectives of metaproteomic data analysis

R Heyer, K Schallert, R Zoun, B Becher, G Saake… - Journal of …, 2017 - Elsevier
In nature microorganisms live in complex microbial communities. Comprehensive taxonomic
and functional knowledge about microbial communities supports medical and technical …

A semi-tryptic peptide centric metaproteomic mining approach and its potential utility in capturing signatures of gut microbial proteolysis

Z Yan, F He, F Xiao, H He, D Li, L Cong, L Lin, H Zhu… - Microbiome, 2021 - Springer
Background Proteolysis regulation allows gut microbes to respond rapidly to dynamic
intestinal environments by fast degradation of misfolded proteins and activation of regulatory …

[引用][C] Development of new technologies to study gut microbiomes

A Palomba - 2014 - Università degli studi di Sassari

Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns

E Timmins-Schiffman, DH May, M Mikan… - The ISME …, 2017 - academic.oup.com
Environmental meta-omics is rapidly expanding as sequencing capabilities improve,
computing technologies become more accessible, and associated costs are reduced. The in …

Metaproteomics: a strategy to study the taxonomy and functionality of the gut microbiota

Y Wang, Y Zhou, X Xiao, J Zheng, H Zhou - Journal of proteomics, 2020 - Elsevier
The gut microbiota is the largest and most complex microbial community in the human body.
Host-gut microbiota interactions have significant implications on health and disease. The …

[PDF][PDF] Building the Unipept Ecosystem: empowering high-throughput metaproteomics data analysis for characterizing complex microbial communities

P Verschaffelt - 2023 - backoffice.biblio.ugent.be
The research presented in this PhD thesis is situated at the overlap of computer science and
biotechnology. In order to fully understand and grasp the concepts that are presented …

An aquatic microbial metaproteomics workflow: From cells to tryptic peptides suitable for tandem mass spectrometry-based analysis

D Colatriano, DA Walsh - JoVE (Journal of Visualized Experiments), 2015 - jove.com
Meta-omic technologies such as metagenomics, metatranscriptomics and metaproteomics
can aid in the understanding of microbial community structure and metabolism. Although …

Metaproteomics of our microbiome—developing insight in function and activity in man and model systems

CA Kolmeder, WM de Vos - Journal of proteomics, 2014 - Elsevier
We are all colonized by a large microbiome, a complex set of microbes that have intimate
associations with us. Culture-based approaches have provided insights in the complexity of …