Promising Antifungal Molecules against Mucormycosis Agents Identified from Pandemic Response Box®: In Vitro and In Silico Analyses

MIDS Xisto, R Rollin-Pinheiro, Y de Castro-Almeida… - Journal of Fungi, 2023 - mdpi.com
Mucormycosis is considered concerning invasive fungal infections due to its high mortality
rates, difficult diagnosis and limited treatment approaches. Mucorales species are highly …

Mucormycosis: A hidden mystery of fungal infection, possible diagnosis, treatment and development of new therapeutic agents

MK Hussain, S Ahmed, A Khan, AJ Siddiqui… - European Journal of …, 2023 - Elsevier
Mucormycosis is a fungal infection which got worsens with time if not diagnosed and treated.
The current COVID-19 pandemic has association with fungal infection specifically with …

In silico prediction and structure-based multitargeted molecular docking analysis of selected bioactive compounds against mucormycosis

P Madanagopal, N Ramprabhu… - Bulletin of the National …, 2022 - Springer
Background During the second wave of the COVID-19 pandemic, an unusual increase in
cases of mucormycosis was observed in India, owing to immunological dysregulation …

Drug repurposing of triazoles against mucormycosis using molecular docking: a short communication

S Mhatre, V Patravale - Computers in Biology and Medicine, 2021 - Elsevier
Background Mucormycosis, a fungal infection caused by Rhizopus species is on the rise in
COVID-19 patients as a result of their suppressed immunity. The current therapies include …

Comprehensive Review on the Virulence Factors and Therapeutic Strategies with the Aid of Artificial Intelligence against Mucormycosis

M Tanwar, A Singh, TP Singh, S Sharma… - ACS Infectious …, 2024 - ACS Publications
Mucormycosis, a rare but deadly fungal infection, was an epidemic during the COVID-19
pandemic. The rise in cases (COVID-19-associated mucormycosis, CAM) is attributed to …

[HTML][HTML] In vitro antifungal activity of MMV Pathogen Box® compounds alone or in combination with antifungal drugs against mucormycosis agents

F Almeida-Silva, PH Tenório-Alvarenga… - Current Research in …, 2024 - Elsevier
Mucormycosis is a severe fungal infection that demands immediate and decisive
intervention upon suspicion. The causative agents of mucormycosis exhibit inherent …

An extensive review on antifungal approaches in the treatment of mucormycosis

HS Chaudhari, OS Palkar… - … of Biochemical and …, 2023 - Wiley Online Library
During the period of COVID‐19, the occurrences of mucormycosis in immunocompromised
patients have increased significantly. Mucormycosis (black fungus) is a rare and rapidly …

Novel 2-aryl-4-aryloxyquinoline-based fungistatics for Mucor circinelloides. Biological evaluation of activity, QSAR and docking study

PD Nahide, C Alba-Betancourt… - Bioorganic & Medicinal …, 2022 - Elsevier
Zygomycetes are ubiquitous saprophytes in natural environments which transform organic
matter. Some zygomycetes of gender Mucor have attracted interest in health sector. Due to …

Triumvirate to treat mucormycosis: Interplay of pH, metal ions and antifungal drugs

B Kapoor, RS Kochhar, M Gulati, P Rani, R Gupta… - Medical …, 2022 - Elsevier
Mucormycosis is a rare fungal infection mainly affecting immunocompromised patients.
Recently, an alarming rise in cases of mucormycosis was observed in patients undergoing …

[HTML][HTML] Targeting mucormycosis polyprotein (RVT_1 region) through antifungal phytochemicals: An in-silico perspective

A Banik, SR Ahmed, H Marma, S Sinha… - Informatics in Medicine …, 2022 - Elsevier
Mucormycosis has become a global issue due to its potential to infect and destroy organs,
as well as its high fatality rate. Co-infecting with Covid 19 or when infecting after Covid 19, it …